Association between serosal intestinal microcirculation and blood pressure during major abdominal surgery

In clinical practice, blood pressure is used as a resuscitation goal on a daily basis, with the aim of maintaining adequate perfusion and oxygen delivery to target organs. Compromised perfusion is often indicated as a key factor in the pathophysiology of anastomotic leakage. This study was aimed at...

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Bibliographic Details
Published in:Journal of intensive medicine 2021-07, Vol.1 (1), p.59-64
Main Authors: Tavy, Arthur LM, de Bruin, Anton FJ, Boerma, E Christiaan, Ince, Can, Hilty, Matthias P, Noordzij, Peter G, Boerma, Djamila, van Iterson, Mat
Format: Article
Language:English
Subjects:
Abdominal surgery
Handheld vital microscopy
Hemodynamic management
Intestinal microcirculation
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Summary:In clinical practice, blood pressure is used as a resuscitation goal on a daily basis, with the aim of maintaining adequate perfusion and oxygen delivery to target organs. Compromised perfusion is often indicated as a key factor in the pathophysiology of anastomotic leakage. This study was aimed at assessing the extent to which the microcirculation of the bowel coheres with blood pressure during abdominal surgery. We performed a prospective and observational cohort study. In patients undergoing abdominal surgery, the serosal microcirculation of either the small intestine or the colon was visualized using handheld vital microscopy (HVM). From the acquired HVM image sequences, red blood cell velocity (RBCv) and total vessel density (TVD) were calculated using MicroTools and AVA software, respectively. The association between microcirculatory parameters and blood pressure was assessed using Pearson's correlation analysis. We considered a two-sided P-value of
ISSN:2667-100X
2667-100X
DOI:10.1016/j.jointm.2021.03.003