Unusual presentation of systemic lupus erythematosus

Bullous systemic lupus erythematosus is a rare distinctive subepidermal blistering disorder that can occur in patients with systemic lupus erythematosus (SLE). It is histologically characterized by a neutrophil-predominant infiltrate in the subepidermal region with deposition of immunoglobulins (IgG...

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Bibliographic Details
Published in:Saudi journal of kidney diseases and transplantation 2017-05, Vol.28 (3), p.653-656
Main Authors: Bande, Sujeeth Reddy, Gireesh, M. S., Gurudev, Vijay Varma, K. C., Mahesh, E., Madhyastha, Parampalli Rakesh
Format: Article
Language:English
Subjects:
Biopsy
Care and treatment
Case studies
Diagnosis
Immunoglobulins
Lupus
Nephritis
Nephrology
Patients
Skin
Systemic lupus erythematosus
Ulcers
الأمراض
التشخيص
الجلد
الذئبة الحمامية
الكولاجين
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Description
Summary:Bullous systemic lupus erythematosus is a rare distinctive subepidermal blistering disorder that can occur in patients with systemic lupus erythematosus (SLE). It is histologically characterized by a neutrophil-predominant infiltrate in the subepidermal region with deposition of immunoglobulins (IgG, IgA, IgM), C3, and auto-antibodies against collagen VII. Herein, we report a case of a 13-year-old girl who presented with bullous SLE and Class III lupus nephritis, which is extremely rare at this age.
ISSN:1319-2442
2320-3838
DOI:10.4103/1319-2442.206468