Clinical utility of landiolol for use in coronary CT angiography

Although remarkable advancement in computed tomography (CT) has been achieved, heart rate control is important to maintain an optimal image quality in coronary CT angiography. Oral or intravenous β-blockers are used as premedication for this purpose. Landiolol was developed as a β-blocker with very...

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Bibliographic Details
Published in:Research reports in clinical cardiology 2015-01, Vol.6 (default), p.145-152
Main Authors: Tomizawa, Nobuo, Hayakawa, Yayoi, Inoh, Shinichi, Nojo, Takeshi, Nakamura, Sunao
Format: Article
Language:English
Subjects:
Cardiac arrhythmia
Cardiology
Cardiovascular disease
Care and treatment
Contrast agents
Coronary heart disease
Coronary vessels
CT imaging
Diagnosis
Electrocardiography
Heart rate
Medical imaging
Methods
Quality
Surgery
Tomography
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Summary:Although remarkable advancement in computed tomography (CT) has been achieved, heart rate control is important to maintain an optimal image quality in coronary CT angiography. Oral or intravenous β-blockers are used as premedication for this purpose. Landiolol was developed as a β-blocker with very high cardioselectivity (β1/β2 =255) and short half-life (4 minutes). In this review, we report the pharmacological features and usage of landiolol and also its effects on heart rate and image quality in coronary CT angiography. In addition, we discuss the safety of landiolol. Keywords: coronary computed tomography angiography, heart rate, image quality
ISSN:1179-8475
1179-8475
DOI:10.2147/RRCC.S77559