Quantification of atherosclerotic plaque volume in coronary arteries by computed tomographic angiography in subjects with and without diabetes

• Published in: Chinese medical journal 2020-04, Vol.133 (7), p.773-778
• Main Authors: Hou, Zhi-Hui, Lu, Bin, Li, Zhen-Nan, An, Yun-Qiang, Gao, Yang, Yin, Wei-Hua, Budoff, Matthew J.
• Format: Article
• Language: English
• Subjects: Aged; Atherosclerosis; Blood pressure; Calcification; Cardiovascular disease; Computed Tomography Angiography - methods; Coronary Artery Disease - diagnostic imaging; Coronary vessels; Coronary Vessels - diagnostic imaging; Diabetes; Family medical history; Female; Glucose; Heart; Humans; Lipids; Male; Medical imaging; Middle Aged; Original; Patients; Plaque, Atherosclerotic - diagnostic imaging; Risk Factors; Veins & arteries
• ISSN: 0366-6999; 2542-5641
• DOI: 10.1097/CM9.0000000000000733

Diabetes mellitus (DM) is considered a cardiovascular risk factor. The aim of this study was to analyze the prevalence and volume of coronary artery plaque in patients with diabetes mellitus (DM) vs. those without DM. This study recruited consecutive patients who underwent coronary computed tomography (CT) angiography (CCTA) between October 2016 and November 2017. Personal information including conventional cardiovascular risk factors was collected. Plaque phenotypes were automatically calculated for volume of different component. The volume of different plaque was compared between DM patients and those without DM. Among 6381 patients, 931 (14.59%) were diagnosed with DM. The prevalence of plaque in DM subjects was higher compared with nondiabetic group significantly (48.34% vs. 33.01%, χ = 81.84, P