Impact of PM2.5 exposure on mortality and tumor recurrence in resectable non-small cell lung carcinoma

• Published in: Scientific reports 2024-10, Vol.14 (1), p.24660-9, Article 24660
• Main Authors: Kosanpipat, Bongkotmas, Wongwut, Thanida, Norrasan, Natthawat, Watthanawongsa, Parada, Phinyo, Phichayut, Saeteng, Somcharoen, Siwachat, Sophon, Chewaskulyong, Busyamas, Tantraworasin, Apichat
• Format: Article
• Language: English
• Subjects: 631/67; 692/308; 692/499; 692/700; Aged; Air pollution; Carcinoma, Non-Small-Cell Lung - mortality; Carcinoma, Non-Small-Cell Lung - pathology; Carcinoma, Non-Small-Cell Lung - surgery; Cell survival; Complications; Environmental Exposure - adverse effects; Female; Hospital Mortality; Humanities and Social Sciences; Humans; In-hospital mortality; Long-term survival; Lung cancer; Lung carcinoma; Lung Neoplasms - mortality; Lung Neoplasms - pathology; Lung Neoplasms - surgery; Male; Middle Aged; Mortality; multidisciplinary; Neoplasm Recurrence, Local; Non-small cell lung carcinoma; Particular matter; Particulate matter; Particulate Matter - adverse effects; Particulate Matter - analysis; Postoperative; Regression analysis; Risk Factors; Science; Science (multidisciplinary); Small cell lung carcinoma; Tumors
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-024-76696-0

This study aimed to explore the impact of PM 2.5 exposure on survival, post-operative outcomes, and tumor recurrence in resectable non-small cell lung cancer (NSCLC) patients. The study cohort comprised 587 patients at Chiang Mai University Hospital between January 1, 2010, and December 31, 2017. Patients were categorized based on their residents’ average PM 2.5 concentration into two groups: exposed (PM 2.5 ≥ 25 µg/m3 annual mean) and unexposed (PM 2.5