Novel Approaches in Diagnosing the Role of Inflammation in the Onset Cardiovascular Disorders

There are a number of chemical mediators and pathways involved in the inflammatory onset of cardiovascular disorders. [...]from a therapeutic point of view, it would be most important to focus on the active mediators of inflammation and apoptosis and to manipulate these in order to improve cell func...

Full description

Saved in:
Bibliographic Details
Published in:Mediators of inflammation 2018-01, Vol.2018, p.8234063-2
Main Authors: Doroszko, Adrian, Dobrowolski, Piotr, Radziwon-Balicka, Aneta, Skomro, Robert
Format: Article
Language:English
Subjects:
Animals
Apoptosis
Atherosclerosis
Autophagy
Biomarkers
Biomarkers - blood
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - blood
Cardiovascular Diseases - pathology
Care and treatment
Cell survival
Cholesterol
Cryotherapy
Diabetes
Diagnosis
Endothelial cells
Endothelium
Humans
Hypertension
Inflammation
Inflammation - blood
Inflammation - pathology
Kinases
Metabolites
Nitric oxide
Nitric-oxide synthase
Oxidative stress
Pathogenesis
Selenoproteins - blood
Sepsis
TOR protein
Tumor necrosis factor
Tumor necrosis factor-TNF
Tumors
Type 2 diabetes
Umbilical vein
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:There are a number of chemical mediators and pathways involved in the inflammatory onset of cardiovascular disorders. [...]from a therapeutic point of view, it would be most important to focus on the active mediators of inflammation and apoptosis and to manipulate these in order to improve cell function and survival. S. Cui et al. demonstrated that the upregulation of SelS enhances the levels of nitric oxide and endothelial nitric oxide synthase in tumour necrosis factor-α-treated human umbilical vein endothelial cells. [...]the mTOR pathway seems to play an important role in myocardial dysfunction induced by sepsis.
ISSN:0962-9351
1466-1861
DOI:10.1155/2018/8234063