Streptomyces infection in Cushing syndrome: A case report and literature review

Streptomyces are saprophytic soil organisms rarely known to cause invasive infections. Streptomyces is the largest genus, producing antibacterial, antifungal and antiparasitic drugs. The case was a 24-year-old man, admitted for sudden dyspnea, fever and sputum and decreased sound in the left lung. T...

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Bibliographic Details
Published in:Advanced biomedical research 2014, Vol.3 (1), p.26-26
Main Authors: Ataiekhorasgani, Masoud, Jafaripozve, Nasim, Zaerin, Omid
Format: Article
Language:English
Subjects:
Acne
Antibiotics
Bacteria
Bacterial infections
Biopsy
Care and treatment
Case Report
Case studies
Complications and side effects
Cushing syndrome
Diagnosis
Gram-positive bacteria
Health aspects
HIV
Human immunodeficiency virus
Infections
Insect bites
Laboratories
NMR
Nuclear magnetic resonance
Organisms
pulmonary infection
Sarcoidosis
Streptomyces
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Summary:Streptomyces are saprophytic soil organisms rarely known to cause invasive infections. Streptomyces is the largest genus, producing antibacterial, antifungal and antiparasitic drugs. The case was a 24-year-old man, admitted for sudden dyspnea, fever and sputum and decreased sound in the left lung. The chest X-ray showed hydropneumothorax. After chest tube insertion, lung expansion did not happen. Pleural effusion was exudative with gram-positive bacillus and Streptomyces in culture. Owing to symptoms of Cushing in history, examination and laboratory work-up for Cushing was done and finally he underwent bilateral adrenalectomy. The patient was on antibiotic broad spectrum antibiotic and then was changed to antibiotic as organism was sensitive to and discharged with clarithromycin for 6 months. Streptomyces happens in immunodeficient patient. Diagnosis is based on culture and contamination was ruled out. Treatment period is longer for patients owing to slow growing nature.
ISSN:2277-9175
2277-9175
DOI:10.4103/2277-9175.124672