Biological Properties, Health Benefits and Enzymatic Modifications of Dietary Methoxylated Derivatives of Cinnamic Acid

Methoxylated derivatives of cinnamic acid play an important role in the formation of the pro-health potential of food products. Numerous reports present them as molecules with strong antimicrobial, antidiabetic, anticancer as well as hepato-, cardio-, and neuroprotective activities. In the last thre...

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Bibliographic Details
Published in:Foods 2021-06, Vol.10 (6), p.1417
Main Authors: Rychlicka, Magdalena, Rot, Agata, Gliszczyńska, Anna
Format: Article
Language:English
Subjects:
Acids
Alzheimer's disease
Antiinfectives and antibacterials
Antioxidants
Bioavailability
Biological activity
Biological properties
Cancer
Chemical compounds
Cinnamic acid
Coffee
Diabetes mellitus
Drug dosages
Enzymes
Food
Food industry
Food science
Fruits
lipids
methoxylated derivatives of cinnamic acid
Neuroprotection
Pathogens
Pharmaceutical industry
Pharmacokinetics
Pharmacology
phospholipids
Polyphenols
Review
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Summary:Methoxylated derivatives of cinnamic acid play an important role in the formation of the pro-health potential of food products. Numerous reports present them as molecules with strong antimicrobial, antidiabetic, anticancer as well as hepato-, cardio-, and neuroprotective activities. In the last three decades, many research groups have tried to extend the practical application of these molecules as therapeutic and antioxidant agents extensively studying the methods of their lipophilization as the solution of problems of their low oral bioavailability and rapid metabolism. This article summarizes the latest data of natural sources of occurrence, biological potential and bioavailability of methoxy derivatives of cinnamic acids. Metabolism and pharmacokinetics of this group of dietary compounds are also extensively discussed as well as reviewing the methods of their chemical and enzymatic lipophilization in the aspect of their use in food and pharmaceutical industries.
ISSN:2304-8158
2304-8158
DOI:10.3390/foods10061417