Vitamin D Deficiency Is Associated with Endoscopic Severity in Patients with Crohn’s Disease

Background and Aims. Vitamin D deficiency is common in patients with Crohn’s disease and is associated with disease activity. Relationship between vitamin D and endoscopic disease activity is unknown. The aim of the study is to determine the association between vitamin D status and endoscopic diseas...

Full description

Saved in:
Bibliographic Details
Published in:Gastroenterology research and practice 2017-01, Vol.2017 (2017), p.1-5
Main Authors: Cao, Qian, Liu, Jing, Lin, Ziwen, Ye, Lingna
Format: Article
Language:English
Subjects:
Care and treatment
Clinical medicine
Colon
Colonoscopy
Complications and side effects
Crohn's disease
Development and progression
Diagnosis
Endoscopic surgery
Endoscopy
FDA approval
Gastroenterology
Gastrointestinal mucosa
Gastrointestinal system
Health aspects
Hospitals
Inflammation
Inflammatory bowel disease
Nutrition research
Patients
Risk factors
Ulcers
Variables
Vitamin D
Vitamin D deficiency
Vitamin deficiency
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background and Aims. Vitamin D deficiency is common in patients with Crohn’s disease and is associated with disease activity. Relationship between vitamin D and endoscopic disease activity is unknown. The aim of the study is to determine the association between vitamin D status and endoscopic disease activity in CD patients. Methods. Consecutive hospitalized CD patients from 2014 to 2016 who received vitamin D assessment and colonoscopy were retrospectively evaluated. Clinical disease activity was assessed by Crohn’s disease activity index and C-reactive protein. Endoscopic activity was calculated using simple endoscopic score for Crohn’s disease. Results. Median serum 25OHD level of 131 patients was lower than healthy controls [21.1 nmol/L (11.8–32.3) versus 49.9 nmol/L (44.9–57.4), P=0.007]. 125 (95%) patients had vitamin D deficiency and the rest (5%) had vitamin D insufficiency. Serum 25OHD was inversely correlated with CRP (r=−0.308, P
ISSN:1687-6121
1687-630X
DOI:10.1155/2017/4869718