The Association Between the Prevalence, Medication Adherence and Control of Hypertension and the Prevalence of Mild Cognitive Impairment in Rural Northern China: A Cross-Sectional Study

High blood pressure is one of the main modifiable risk factors for dementia. However, it remains unclear whether lowering the blood pressure effectively prevents cognitive impairment. Our objective was to explore the association between the prevalence, medication adherence and control of hypertensio...

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Published in:Patient preference and adherence 2022-01, Vol.16, p.493-502
Main Authors: Ma, Ling-Yun, He, Fangfang, Liu, Shuai, Wang, Xiao-Dan, Gao, Yanqin, Shi, Zhihong, Niu, Jianping, Ji, Yong
Format: Article
Language:English
Subjects:
Cognition disorders
Complications and side effects
Drug therapy
elderly individuals
Hypertension
medication adherence
mild cognitive impairment
Original Research
Patient compliance
Psychological aspects
Risk factors
Rural aged
Surveys
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Summary:High blood pressure is one of the main modifiable risk factors for dementia. However, it remains unclear whether lowering the blood pressure effectively prevents cognitive impairment. Our objective was to explore the association between the prevalence, medication adherence and control of hypertension and mild cognitive impairment (MCI) among elderly individuals in northern China. A two-stage clustering sampling method was used, and 9036 participants aged ≥65 years were included in the analysis. The Mini-Mental State Examination and activities of daily living were used to assess participants' cognitive function. Demographic characteristics (gender, age, marital status, education level, occupation), history and duration of hypertension, use of antihypertensive medications (AHMs) and its control effect were obtained. The prevalence of MCI in all participants was 18.1%, and the prevalence of MCI was significantly higher in hypertensive subjects than in normotensive subjects (19.7% vs 16.2%,  
ISSN:1177-889X
1177-889X
DOI:10.2147/PPA.S351588