Pregnancy outcomes of the first thawing cycle in “freeze-all” strategy of infertility patients with fever during oocyte recruitment: a matched-pair study

It is currently unknown whether patients with a fever after controlled ovulation during egg retrieval could increase the risk of pelvic infection or not, and fever itself may affect endometrial receptivity or embryo quality with poor pregnancy outcomes. The aim of this study was to analyze the outco...

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Bibliographic Details
Published in:Chinese medical journal 2020-12, Vol.134 (7), p.800-805
Main Authors: Lin, Ming-Mei, Niu, Zi-Ru, Zhang, Hua, Li, Rong
Format: Article
Language:English
Subjects:
Cryopreservation
Female
Fertilization in Vitro
Freezing
Humans
Infertility
Oocyte Retrieval
Oocytes
Original
Ovulation Induction
Pregnancy
Pregnancy Outcome
Pregnancy Rate
Retrospective Studies
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Summary:It is currently unknown whether patients with a fever after controlled ovulation during egg retrieval could increase the risk of pelvic infection or not, and fever itself may affect endometrial receptivity or embryo quality with poor pregnancy outcomes. The aim of this study was to analyze the outcomes of patients with fever during oocyte retrieval after the first frozen-thawed embryo transfer (FET) cycle. This was a 1:3 retrospective paired study matched for age. In this study, 58 infertility patients (Group 1) had a fever during the control ovulation, and the time of the oocyte retrieval was within 72 hours, they underwent ovum pick up and whole embryo freezing ("freeze-all" strategy). The control subjects (Group 2) are 174 patients matched for age who underwent whole embryo freezing for other reasons. The baseline characteristics, clinical data of ovarian stimulation, and outcomes, such as the clinical pregnancy rate, ongoing clinical pregnancy rate were compared between the two groups in the subsequent FET cycle. All patients had no pelvic inflammatory disease after oocyte retrieval. Anti-Mullerian hormone (AMH) levels (4.2 vs. 2.2, P
ISSN:0366-6999
2542-5641
DOI:10.1097/CM9.0000000000001238