Review of cystic and solid tumors of the iris

Iris tumors are broadly classified into cystic or solid lesions. The cystic lesions arise from iris pigment epithelium (IPE) or iris stroma. IPE cysts classically remain stable without need for intervention. Iris stromal cyst, especially those in newborns, usually requires therapy of aspiration, pos...

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Bibliographic Details
Published in:Oman journal of ophthalmology 2013-09, Vol.6 (3), p.159-164
Main Authors: Shields, Carol L, Shields, Patrick W, Manalac, Janet, Jumroendararasame, Chaisiri, Shields, Jerry A
Format: Article
Language:English
Subjects:
Cyst
eye
iris
melanoma
metastasis
nevus
Review
tumor
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Summary:Iris tumors are broadly classified into cystic or solid lesions. The cystic lesions arise from iris pigment epithelium (IPE) or iris stroma. IPE cysts classically remain stable without need for intervention. Iris stromal cyst, especially those in newborns, usually requires therapy of aspiration, possibly with alcohol-induced sclerosis, or surgical resection. The solid tumors included melanocytic and nonmelanocytic lesions. The melanocytic iris tumors include freckle, nevus (including melanocytoma), Lisch nodule, and melanoma. Information from a tertiary referral center revealed that transformation of suspicious iris nevus to melanoma occurred in 4% by 10 years and 11% by 20 years. Risk factors for transformation of iris nevus to melanoma can be remembered using the ABCDEF guide as follows: A=age young (
ISSN:0974-620X
0974-7842
DOI:10.4103/0974-620x.122269