The effect of immunotherapy with gynandropsis gynandra pollen in atopic asthma patients

Background: Immunotherapy (IT) was first described by Noon and Freeman in 1911. The mechanism underlying successful immunotherapy is however not known. The protection from allergy is achieved long before IgE levels are de-creased, and they are indeed not frequently increased. Continued therapy may d...

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Bibliographic Details
Published in:Lung India 2007-01, Vol.24 (4), p.124-127
Main Authors: Latha, GSuman, Lakshmi, VVijaya, Rani, HSurekha, Murthy, KJR
Format: Article
Language:English
Subjects:
Gynandropsis (G. gynandra)
IgE
Immunotherapy (IT)
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Summary:Background: Immunotherapy (IT) was first described by Noon and Freeman in 1911. The mechanism underlying successful immunotherapy is however not known. The protection from allergy is achieved long before IgE levels are de-creased, and they are indeed not frequently increased. Continued therapy may decrease IgE and skin reaction, although it may take years. Objective: The evaluation of effect of immunotherapy with specific pollen Gyn-andropsis gynandra. Material & Methods: Clinical subjects like skin test response, symptoms score, drugs intake and total sIgE levels were studied in sixty patients. Results: Both immediate and delayed skin test responses were highly significant. The intensity of symptoms score and medication was reduced and total sIgE levels were inconsistent after the course of IT. Conclusion: The decrease in clinical subjects may be attributed to the beneficial effect of immunotherapy with Gynandropsis gynandra.
ISSN:0970-2113
0974-598X
DOI:10.4103/0970-2113.44375