The roles of T cells in psoriasis

Psoriasis is a recurring inflammatory skin condition characterized by scaly, red patches on the skin. It affects approximately 3% of the US population and is associated with histological changes such as epidermal hyperplasia, increased blood vessel proliferation, and infiltration of leukocytes into...

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Bibliographic Details
Published in:Frontiers in immunology 2023-10, Vol.14, p.1081256-1081256
Main Authors: Zhang, Peng, Su, Yuwen, Li, Siying, Chen, Hui, Wu, Ruifang, Wu, Haijing
Format: Article
Language:English
Subjects:
cytokines
Immunology
psoriasis
T lymphocytes
targeted therapies
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Summary:Psoriasis is a recurring inflammatory skin condition characterized by scaly, red patches on the skin. It affects approximately 3% of the US population and is associated with histological changes such as epidermal hyperplasia, increased blood vessel proliferation, and infiltration of leukocytes into the skin’s dermis. T cells, which are classified into various subtypes, have been found to play significant roles in immune-mediated diseases, particularly psoriasis. This paper provides a review of the different T lymphocyte subtypes and their functions in psoriasis, as well as an overview of targeted therapies for treating psoriasis.
ISSN:1664-3224
1664-3224
DOI:10.3389/fimmu.2023.1081256