Inhibitory effects of Ficus carica and Olea europaea on pro-inflammatory cytokines: A review

(fig) and (olive) are valuable nutritional plants that are widely used in diet and traditional medicine. Different parts of the plants such as fruit and leaves contain beneficial compounds with diverse pharmacological properties, among which anti-inflammatory activities are remarkable. The purpose o...

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Bibliographic Details
Published in:Iranian journal of basic medical sciences 2022-03, Vol.25 (3), p.268-275
Main Authors: Rezagholizadeh, Lotfollah, Aghamohammadian, Maryam, Oloumi, Mahya, Banaei, Shokofeh, Mazani, Mohammad, Ojarudi, Masoud
Format: Article
Language:English
Subjects:
Biochemistry
Carbohydrates
Coronaviruses
COVID-19
cytokine
Cytokine storm
Cytokines
Enzymes
ficus carica
Flavonoids
Infections
Inflammation
Inflammatory diseases
Kinases
Medicine
olea europaea
Olives
Pathogens
Pathophysiology
Physiology
Phytochemicals
Polyphenols
Review
Roles
tnf-α
Tumor necrosis factor-TNF
Viral infections
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Summary:(fig) and (olive) are valuable nutritional plants that are widely used in diet and traditional medicine. Different parts of the plants such as fruit and leaves contain beneficial compounds with diverse pharmacological properties, among which anti-inflammatory activities are remarkable. The purpose of this review is to discuss the anti-inflammatory effects of and with emphasis on their impact on pivotal pro-inflammatory cytokines including IL-1, IL-6, and TNF-α. To prepare the present review, the sites utilized included Scopus, PubMed, Science Direct, and Google Scholar and studied relevant articles from 2000 until 2021. As a result, we observed that most of the compounds in fig and olive including polyphenols, flavonoids, etc., exert their anti-inflammatory effects through inhibiting or decreasing pro-inflammatory cytokines. Moreover, some natural antioxidants are common between these two plants. We suggest that consuming figs and olives simultaneously or alone can be useful in the prevention or treatment of inflammatory diseases.
ISSN:2008-3866
2008-3874
DOI:10.22038/IJBMS.2022.60954.13494