Palisaded neutrophilic granulomatous dermatitis: Case report and review of literature

Palisaded neutrophilic granulomatous dermatitis (PNGD) is a rare inflammatory dermatosis. We report a 45-year-old female with a 2-year history of asymptomatic persistent skin lesions. The patient had rheumatoid arthritis well controlled with abatacept, methotrexate, and hydroxychloroquine. Multiple...

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Bibliographic Details
Published in:Journal of dermatology & dermatologic surgery 2020-01, Vol.24 (1), p.54-56
Main Authors: Alzahrani, Bashair, Tayeb, Anas, Abdulkarim, Johara, Bahadur, Ruba, Almontashiri, Abdullah, Al Hawsawi, Khalid
Format: Article
Language:English
Subjects:
interstitial granulomatous dermatitis with arthritis
palisaded neutrophilic granulomatous dermatosis
rheumatoid papules
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Summary:Palisaded neutrophilic granulomatous dermatitis (PNGD) is a rare inflammatory dermatosis. We report a 45-year-old female with a 2-year history of asymptomatic persistent skin lesions. The patient had rheumatoid arthritis well controlled with abatacept, methotrexate, and hydroxychloroquine. Multiple nonscaly umbilicated papules with crusted center were scattered on her abdomen, chest wall, and back. Biopsy showed pandermal infiltrate of neutrophils and areas of basophilic degenerated collagen surrounded by palisades of histiocytes, neutrophils deep in the dermis, and subcutaneous fat. A diagnosis of PNGD was made. The patient was treated with betamethasone dipropionate (0.05%) ointment and oral colchicine with good improvement.
ISSN:2352-2410
2352-2429
DOI:10.4103/jdds.jdds_55_19