Extensively drug-resistant Pseudomonas aeruginosa panophthalmitis from contaminated artificial tears

Pseudomonas aeruginosa is one of the common gram-negative organisms that cause severe invasive infections in different organ systems. P. aeruginosa has unique intrinsic mechanisms to develop antimicrobial resistance quickly, making it extremely difficult to treat. We report a case of extensively dru...

Full description

Saved in:
Bibliographic Details
Published in:IDCases 2023-01, Vol.33, p.e01839, Article e01839
Main Authors: Wang, Taylor, Jain, Sumeet, Glidai, Yoav, Dua, Prachi, Dempsey, Katharine S., Shakin, Eric, Chu, David S., Epstein, Marcia, Ha, Lawrence G.
Format: Article
Language:English
Subjects:
Case Report
Endophthalmitis
GES resistance gene
Multidrug-resistant organism
Pseudomonas aeruginosa
VIM resistance gene
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Pseudomonas aeruginosa is one of the common gram-negative organisms that cause severe invasive infections in different organ systems. P. aeruginosa has unique intrinsic mechanisms to develop antimicrobial resistance quickly, making it extremely difficult to treat. We report a case of extensively drug-resistant (XDR) P. aeruginosa panophthalmitis due to contaminated artificial tears. This report investigates the role of systemic and intravitreal antimicrobials, summarizes the resistance mechanisms of P. aeruginosa, and provides an overview on cefiderocol, a novel antimicrobial that targets multidrug-resistant (MDR) and XDR Gram-negative pathogens.
ISSN:2214-2509
2214-2509
DOI:10.1016/j.idcr.2023.e01839