Nonsurgical Approach to Isolated Pancreatic Metastatic Malignant Melanoma: A Case Report and Review of the Literature

Isolated pancreatic metastases from melanoma are rare with high mortality rate and account for less than 1% of metastatic melanomas. Treatment options are limited with highest overall survival reported in those with complete surgical resection. Of cases reported in the literature with nonsurgical ma...

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Bibliographic Details
Published in:JIM - high impact case reports 2022, Vol.10, p.23247096221111763-23247096221111763
Main Authors: Trad, George, Sheikhan, Nazanin, Nguyen, Andrew, Hader, Ismail
Format: Article
Language:English
Subjects:
Case Report
Case reports
Humans
Immunotherapy
Interferons - therapeutic use
Melanoma
Melanoma - pathology
Melanoma - therapy
Melanoma, Cutaneous Malignant
Metastasis
Pancreas
Pancreatic Neoplasms - secondary
Pancreatic Neoplasms - therapy
Skin Neoplasms - pathology
Skin Neoplasms - therapy
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Summary:Isolated pancreatic metastases from melanoma are rare with high mortality rate and account for less than 1% of metastatic melanomas. Treatment options are limited with highest overall survival reported in those with complete surgical resection. Of cases reported in the literature with nonsurgical management, highest length of survival was reported to be 10 months. We report a case of malignant melanoma with isolated pancreatic metastasis treated with interferon therapy and immunotherapy, with evidence of progressive tumor shrinkage and survival at 38 months.
ISSN:2324-7096
2324-7096
DOI:10.1177/23247096221111763