Characteristics of HIV pre-exposure prophylaxis users at first PrEP counselling visit: the CSL-PrEP cohort

Pre-exposure prophylaxis (PrEP) is effective for HIV prevention and is mostly used by men who have sex with men (MSM). The aim of this study was to describe the characteristics of a cohort of PrEP users at first PrEP counselling visits (baseline, BL). Cross-sectional study of a cohort of MSM receivi...

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Bibliographic Details
Published in:BMJ open 2022-12, Vol.12 (12), p.e067261-e067261
Main Authors: Nozza, Silvia, Raccagni, Angelo Roberto, Lolatto, Riccardo, Ceccarelli, Daniele, Galli, Laura, Alberton, Francesca, Bruzzesi, Elena, Canetti, Diana, Strano, Martina, Ripa, Marco, Bertoni, Costanza, Castagna, Antonella
Format: Article
Language:English
Subjects:
Adult
Chlamydia
Counseling
Cross-Sectional Studies
Disease prevention
Gays & lesbians
Gonorrhea
Gonorrhea - epidemiology
HIV
HIV Infections - drug therapy
HIV Infections - epidemiology
HIV Infections - prevention & control
HIV/AIDS
Homosexuality, Male
Human immunodeficiency virus
Humans
Infections
Infectious diseases
Laboratories
Male
Mens health
Pre-Exposure Prophylaxis - methods
Sexual and Gender Minorities
Sexual behavior
Sexually transmitted diseases
Sexually Transmitted Diseases - epidemiology
Sexually Transmitted Diseases - prevention & control
STD
Syphilis
White people
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Summary:Pre-exposure prophylaxis (PrEP) is effective for HIV prevention and is mostly used by men who have sex with men (MSM). The aim of this study was to describe the characteristics of a cohort of PrEP users at first PrEP counselling visits (baseline, BL). Cross-sectional study of a cohort of MSM receiving PrEP (Centro San Luigi, CSL-PrEP Cohort). Secondary-level sexually transmitted infections (STI) centre in Milan, Italy, from May 2017 to May 2022. Overall, 624 MSM PrEP users were included; most users were Caucasian (97%), attended university (64%), with a median BL age of 34.5 years. Overall, 45% choose the daily-based PrEP regimen, 55% the event-based one. An increasing trend in PrEP counselling visits was observed (p=0.024). The majority had between 10 and 19 partners in the 3 months before BL and 41% were chemsex users. All had a HIV Incidence Risk Index for MSM (HIRI-MSM)>10, 54% between 20 and 29. Overall, 50% had ≥1 previous STI and 22% ≥1 BL STI. BL chlamydia (10%) was often more frequent than in the past (7%). The number of sexual partners was associated with BL chlamydia (p
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2022-067261