Three-Component Reactions of Alkynone o‑Methyloximes, Element Selenium, and Boronic Acids Leading to 4‑Organoselenylisoxazoles

We report an Ag-catalyzed one-pot three-component reaction of alkynone o-methyloxime, element selenium, and boronic acid, providing a facile route to selenated isoxazole product. This protocol features high efficiency, wide substrate scope, and the use of selenium powder as the selenium source.

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Bibliographic Details
Published in:ACS omega 2020-09, Vol.5 (36), p.23358-23363
Main Authors: Wu, Jian, Yang, Ye-Fei, Huang, Xiao-Bo, Gao, Wen-Xia, Zhou, Yun-Bing, Liu, Miao-Chang, Wu, Hua-Yue
Format: Article
Language:English
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Description
Summary:We report an Ag-catalyzed one-pot three-component reaction of alkynone o-methyloxime, element selenium, and boronic acid, providing a facile route to selenated isoxazole product. This protocol features high efficiency, wide substrate scope, and the use of selenium powder as the selenium source.
ISSN:2470-1343
2470-1343
DOI:10.1021/acsomega.0c03254