Management of perioperative anticoagulation in a patient with antiphospholipid antibody syndrome undergoing cardiac surgery: A case report

Patients with Antiphospholipid syndrome (APLS) are at high risk for both bleeding and thrombotic complications during cardiac surgery involving cardiopulmonary bypass (CPB). In this case we present a patient with APLS and Immune Thrombocytopenic Purpura who successfully underwent aortic valve replac...

Full description

Saved in:
Bibliographic Details
Published in:Annals of cardiac anaesthesia 2022-04, Vol.25 (2), p.206-209
Main Authors: Malviya, Sanjana, Deng, Yi, Gilani, Sayyed, Hendon, Alec, Nikolaidis, Melissa, Moseley, Micah
Format: Article
Language:English
Subjects:
Antibodies
Anticardiolipin antibodies
Anticoagulants
Anticoagulants (Medicine)
antifibrinolytics
antiphospholipid syndrome
Aprotinin
Autoimmune diseases
cardiopulmonary bypass
Case Report
Case reports
Coagulation
Coronary artery bypass
Endocarditis
Heart surgery
immune thrombocytopenic purpura
libman-sacks endocarditis
Tranexamic acid
Viral antibodies
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Patients with Antiphospholipid syndrome (APLS) are at high risk for both bleeding and thrombotic complications during cardiac surgery involving cardiopulmonary bypass (CPB). In this case we present a patient with APLS and Immune Thrombocytopenic Purpura who successfully underwent aortic valve replacement (AVR) with CPB despite recent craniotomy for subdural hematoma evacuation. Anticoagulation for CPB was monitored by targeting an Activated Clotting Time (ACT) that was 2× the upper limit of normal. A multidisciplinary approach was essential in ensuring a safe and successful operation.
ISSN:0971-9784
0974-5181
DOI:10.4103/aca.aca_228_20