Risk factors of early pulmonary hypertension and its clinical outcomes in preterm infants: a systematic review and meta-analysis

The aim of this meta-analysis was to determine the incidence and risk factors of early pulmonary hypertension (PHT) in preterm infants and evaluate the association of early PHT with morbidities such as bronchopulmonary dysplasia (BPD), late PHT, and in-hospital mortality. We searched the PubMed (198...

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Bibliographic Details
Published in:Scientific reports 2022-08, Vol.12 (1), p.14186-14186, Article 14186
Main Authors: Kim, Yoo Jinie, Shin, Seung Han, Park, Hye Won, Kim, Ee-Kyung, Kim, Han-Suk
Format: Article
Language:English
Subjects:
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Age
Birth weight
Clinical outcomes
Dysplasia
Heterogeneity
Humanities and Social Sciences
Hypertension
Infants
Low birth weight
Meta-analysis
Mortality
multidisciplinary
Neonates
Newborn babies
Observational studies
Premature babies
Pulmonary hypertension
Risk factors
Science
Science (multidisciplinary)
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Summary:The aim of this meta-analysis was to determine the incidence and risk factors of early pulmonary hypertension (PHT) in preterm infants and evaluate the association of early PHT with morbidities such as bronchopulmonary dysplasia (BPD), late PHT, and in-hospital mortality. We searched the PubMed (1980–2021), Embase (1968–2021), CINAHL (2002–2021), Cochrane library (1989–2021), and KoreaMed (1993–2021). Observational studies on the association between early PHT diagnosed within the first 2 weeks after birth and its clinical outcomes in preterm infants born before 37 weeks of gestation or with very low birth weight (
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-022-18345-y