Immune System Evasion Mechanisms in Staphylococcus aureus: Current Understanding

Staphylococcus aureus is a major human pathogen that may cause a wide range of infections and is a frequent cause of soft tissue and bloodstream infections. It is a successful pathogen due to its collective virulence factors and its ability to evade the host immune systems. The review aims to highli...

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Bibliographic Details
Published in:Journal of pure & applied microbiology : an international research journal of microbiology 2020-12, Vol.14 (4), p.2219-2234
Main Authors: Malak, Hesham A, Abulreesh, Hussein H, Organji, Sameer R, Elbanna, Khaled, Shaaban, Mohammed R, Samreen, Ahmad, Iqbal, Shami, Ashwag, Alshehri, Wafa A, Khalel, Ashjan, Abureesh, Hiyam H, Asiri, Fatimah H, Aldosari, Mohammad S, Almalki, Meshal H.K
Format: Article
Language:English
Subjects:
Health aspects
immune evasion
Immune system
Infection
Methicillin
pathogenesis
Staphylococcus aureus
Staphylococcus aureus infections
virulence
Virulence (Microbiology)
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Summary:Staphylococcus aureus is a major human pathogen that may cause a wide range of infections and is a frequent cause of soft tissue and bloodstream infections. It is a successful pathogen due to its collective virulence factors and its ability to evade the host immune systems. The review aims to highlight how S. aureus destroys and damage the host cells and explains how immune cells can respond to this pathogen. This review may also provide new insights that may be useful for developing new strategy for combating MRSA and its emerging clones such as community-associated methicillin-resistant S. aureus (CA-MRSA).
ISSN:0973-7510
2581-690X
DOI:10.22207/JPAM.14.4.01