Research Progress on Cognitive Frailty in Older Adults with Chronic Kidney Disease

Abstract Background: As the medical challenges posed by the ageing population become increasingly severe, the proportion of older people among patients with chronic kidney disease (CKD) is increasing every year. Summary: The prevalence of frailty in patients with CKD is significantly higher than tha...

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Bibliographic Details
Published in:Kidney & blood pressure research 2024-01, Vol.49 (1), p.302-309
Main Authors: Yuan, Yuqing, Chang, Jing, Sun, Qianmei
Format: Article
Language:English
Subjects:
Aged
ageing
Brain research
Cerebrovascular disease
chronic kidney disease
Cognitive ability
Cognitive Dysfunction - etiology
cognitive frailty
Dementia
Diabetes
Energy consumption
Epidemiology
Flow velocity
Frail Elderly
Frailty
Frailty - complications
Gerontology
haemodialysis
Hemodialysis
Hemodynamics
Humans
Kidney diseases
Memory
Metabolites
Older people
Physiology
Prevalence
Renal Insufficiency, Chronic - complications
Renal Insufficiency, Chronic - psychology
Review Article
Risk factors
Sarcopenia
Stroke
Toxins
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Summary:Abstract Background: As the medical challenges posed by the ageing population become increasingly severe, the proportion of older people among patients with chronic kidney disease (CKD) is increasing every year. Summary: The prevalence of frailty in patients with CKD is significantly higher than that in the general population, and older patients are also a high-risk group for frailty and cognitive impairment. Cognitive frailty, as an important subtype of frailty, is a syndrome characterised by cognitive dysfunction caused by physiological factors, excluding Alzheimer’s disease and other types of dementia. It is characterised by the coexistence of physical frailty and cognitive impairment. Previous studies have mainly focused on cognitive impairment, and there is limited research on cognitive frailty, particularly in older patients with CKD. Key Messages: This article provides a comprehensive review of the concept, epidemiology, screening methods, prevention, and treatment measures and possible pathogenesis of cognitive frailty in patients with CKD.
ISSN:1420-4096
1423-0143
DOI:10.1159/000538689