The amplitude of low-frequency fluctuations is correlated with birth trauma in patients with postpartum post-traumatic stress disorder

Postpartum post-traumatic stress disorder (PP-PTSD) is a severe mental disorder worldwide. In recent years, some studies have reported that PP-PTSD stems from birth trauma. The present study was dedicated in finding ways to predict the occurrence of emergency caesarean section (ECS), trying to analy...

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Bibliographic Details
Published in:Translational psychiatry 2024-08, Vol.14 (1), p.332-9
Main Authors: Chen, Chunlian, Li, Bo, Chai, Liping, Liu, Kai, Zhang, Shufen
Format: Article
Language:English
Subjects:
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Adult
Behavioral Sciences
Biological Psychology
Birth injuries
Brain - diagnostic imaging
Brain - physiopathology
Cesarean Section
Female
Humans
Magnetic Resonance Imaging
Medicine
Medicine & Public Health
Neurosciences
Pharmacotherapy
Post traumatic stress disorder
Postpartum Period - psychology
Pregnancy
Psychiatry
Puerperal Disorders - diagnostic imaging
Puerperal Disorders - physiopathology
Regression analysis
ROC Curve
Stress Disorders, Post-Traumatic - diagnostic imaging
Stress Disorders, Post-Traumatic - physiopathology
Young Adult
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Summary:Postpartum post-traumatic stress disorder (PP-PTSD) is a severe mental disorder worldwide. In recent years, some studies have reported that PP-PTSD stems from birth trauma. The present study was dedicated in finding ways to predict the occurrence of emergency caesarean section (ECS), trying to analyze the methods to reduce incidence of PP-PTSD on this basis, further exploring the neuroimaging changes in PP-PTSD. A total of 245 primiparas with intention of vaginal delivery were recruited. The internal tocodynamometry measurement was performed during labor for all mothers, and respectively taken at 3–5 cm, 5–8 cm, and 8–10 cm of cervical dilation. The receiver operating characteristic (ROC) curve and Binary logistic regression analyses were also performed to identify fetal head descending thrust that might help in the prediction of ECS. Resting-state magnetic resonance imaging (MRI) was performed on 26 patients diagnosed with PP-PTSD of 245 mothers, the amplitude of low-frequency fluctuations (ALFF) technology was used to observe the spontaneous neural activity of all PP-PTSD patients and correlation analyses were performed. We found that the natural delivery rate of mothers with fetal head descending thrust
ISSN:2158-3188
2158-3188
DOI:10.1038/s41398-024-03018-3