Biomedical Applications of Iron Oxide Nanoparticles: Current Insights Progress and Perspectives

The enormous development of nanomaterials technology and the immediate response of many areas of science, research, and practice to their possible application has led to the publication of thousands of scientific papers, books, and reports. This vast amount of information requires careful classifica...

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Bibliographic Details
Published in:Pharmaceutics 2022-01, Vol.14 (1), p.204
Main Authors: Montiel Schneider, María Gabriela, Martín, María Julia, Otarola, Jessica, Vakarelska, Ekaterina, Simeonov, Vasil, Lassalle, Verónica, Nedyalkova, Miroslava
Format: Article
Language:English
Subjects:
Atoms & subatomic particles
Biocompatibility
Cancer therapies
Contrast agents
Efficiency
Hyperthermia
Ligands
Magnetic fields
Magnetic resonance imaging
magnetite
Metals
Morphology
MRI
multitherapy
Nanoparticles
Nanostructured materials
Nanotechnology
Particle size
Quantum dots
Review
SPIONS
theranostics
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Summary:The enormous development of nanomaterials technology and the immediate response of many areas of science, research, and practice to their possible application has led to the publication of thousands of scientific papers, books, and reports. This vast amount of information requires careful classification and order, especially for specifically targeted practical needs. Therefore, the present review aims to summarize to some extent the role of iron oxide nanoparticles in biomedical research. Summarizing the fundamental properties of the magnetic iron oxide nanoparticles, the review's next focus was to classify research studies related to applying these particles for cancer diagnostics and therapy (similar to photothermal therapy, hyperthermia), in nano theranostics, multimodal therapy. Special attention is paid to research studies dealing with the opportunities of combining different nanomaterials to achieve optimal systems for biomedical application. In this regard, original data about the synthesis and characterization of nanolipidic magnetic hybrid systems are included as an example. The last section of the review is dedicated to the capacities of magnetite-based magnetic nanoparticles for the management of oncological diseases.
ISSN:1999-4923
1999-4923
DOI:10.3390/pharmaceutics14010204