Calcifying pseudoneoplasms of the neuraxis (CAPNON): The great tumor mimicker

Calcifying pseudoneoplasms of the neuraxis (CAPNON) are very rare intracranial lesions with less than 50 cases reported in literature. These are non-neoplastic in etiology and despite having unique imaging characteristics, are often misdiagnosed as a neoplastic condition like meningioma, chordoma an...

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Bibliographic Details
Published in:Radiology case reports 2022-09, Vol.17 (9), p.3157-3161
Main Authors: Greco, Elena, Elmandouh, Omar, Desai, Amit, Bhatt, Alok, Vibhute, Prasanna, Aggarwal, Amit
Format: Article
Language:English
Subjects:
Calcifying
Case Report
MRI
Pseudoneoplasms
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Description
Summary:Calcifying pseudoneoplasms of the neuraxis (CAPNON) are very rare intracranial lesions with less than 50 cases reported in literature. These are non-neoplastic in etiology and despite having unique imaging characteristics, are often misdiagnosed as a neoplastic condition like meningioma, chordoma and gliomas. These do not have any predilection for any age, gender or intracranial location and can be seen in a wide range of age groups. Despite having an imaging overlap with neoplastic conditions, CAPNONs have classic histopathologic findings including chondromyxoid matrix, palisading spindle cells and calcific or ossific metaplasia. As more cases are being described in literature the imaging features are also being better defined. We discuss the clinical, imaging and histopathological findings of 2 cases of CAPNON mimicking posterior fossa meningioma and glial neoplasm.
ISSN:1930-0433
1930-0433
DOI:10.1016/j.radcr.2022.05.082