Feasibility and acceptability of a dengue self-monitoring system to reduce treatment delay in Malaysia: A single-centre pilot randomised controlled trial

• Published in: Digital health 2024-01, Vol.10, p.20552076241277710
• Main Authors: Ng, Wei Leik, Ng, Chirk Jenn, Teo, Chin Hai, Ang, Tan Fong, Lee, Yew Kong, Abdul Hadi, Haireen, Chiang, De Min, Mohd Noor, Mohd Khairi, Syed Omar, Sharifah Faridah, Ong, Hang Cheng, Wong, Pui Li, Kukreja, Anjanna, Chiew, Thiam Kian, Ong, Sim Ying, Noor Azhar, Abdul Muhaimin
• Format: Article
• Language: English
• ISSN: 2055-2076; 2055-2076
• DOI: 10.1177/20552076241277710

Most dengue cases are managed in an outpatient setting, where patients are advised to return to the clinic daily for monitoring. Some patients can develop severe dengue at home and fail to recognise the deterioration. An application called DengueAid was designed as a self-monitoring tool for patients to reduce delay in seeking timely treatment. This study aimed to assess the feasibility of conducting a randomised controlled trial to determine the effectiveness of the DengueAid application. Dengue patients were recruited from a public health clinic in Malaysia and randomised to either use the DengueAid application plus standard care for dengue or receive only the standard care. The outcomes evaluated were the (1) feasibility of recruitment, data collection and follow-up procedures; (2) preliminary clinical outcome measures; and (3) acceptability of DengueAid. Qualitative interviews were conducted for participants in the intervention arm to assess the acceptability of DengueAid. Thirty-seven patients were recruited with 97% (  = 36) retention rates. The recruitment rate was low (63% refusal rate,  = 62/99) with difficulty in data collection and follow-up due to the variable interval of care for dengue in an outpatient setting. DengueAid application was acceptable to the participants, but preliminary clinical outcomes and qualitative data suggested limited utility of the application. Unwell conditions of patients and limited access to healthcare are important factors impacting the application's utility. The feasibility trial uncovered issues with recruitment, data collection and follow-up processes. Further research and modification to the application are needed to improve its utility and usability.