International Variations in Surgical Quality of Care in Men With Prostate Cancer: Results From the TrueNTH Global Registry

• Published in: JCO global oncology 2024-05, Vol.10 (10), p.e2300420-e2300420
• Main Authors: Sibert, Nora Tabea, Garin, Olatz, Ferrer, Montserrat, Connor, Sarah E, Graham, Ian D, Litwin, Mark S, Millar, Jeremy, Moore, Caroline M, Nguyen, Anissa V, Paich, Kellie, Kowalski, Christoph
• Format: Article
• Language: English
• Subjects: Aged; Humans; Male; Middle Aged; Prostatectomy - adverse effects; Prostatic Neoplasms - surgery; Quality of Health Care - standards; Quality of Health Care - statistics & numerical data; Quality of Life; Registries - statistics & numerical data; Surveys and Questionnaires; Urinary Incontinence - epidemiology
• ISSN: 2687-8941; 2687-8941
• DOI: 10.1200/GO.23.00420

Functional problems such as incontinence and sexual dysfunction after radical prostatectomy (RP) are important outcomes to evaluate surgical quality in prostate cancer (PC) care. Differences in survival after RP between countries are known, but differences in functional outcomes after RP between providers from different countries are not well described. Data from a multinational database of patients with PC (nonmetastatic, treated by RP) who answered the EPIC-26 questionnaire at baseline (before RP, T0) and 1 year after RP (T1) were used, linking survey data to clinical information. Casemix-adjusted incontinence and sexual function scores (T1) were calculated for each country and provider on the basis of regression models and then compared using minimally important differences (MIDs). A total of 21,922 patients treated by 151 providers from 10 countries were included. For the EPIC-26 incontinence domain, the median adjusted T1 score of countries was 76, with one country performing more than one MID (for incontinence: 6) worse than the median. Eighteen percent of the variance ( ) of incontinence scores was explained by the country of the providers. The median adjusted T1 score of sexual function was 33 with no country performing perceivably worse than the median (more than one MID worse), and 34% ( ) of the variance of the providers' scores could be explained by country. To our knowledge, this is the first comparison of functional outcomes 1 year after surgical treatment of patients with PC between different countries. Country is a relevant predictor for providers' incontinence and sexual function scores. Although the results are limited because of small samples from some countries, they should be used to enhance cross-country initiatives on quality improvement in PC care.