Impaired glomerular filtration rate and associated factors among diabetic mellitus patients with hypertension in referral hospitals, Amhara Regional State, Ethiopia

Impaired glomerular filtration rate is common health problem in diabetic mellitus patients (DM) with hypertension (HTN). It is a major cause of morbidity, mortality, and poor quality of life. There is limited data on the prevalence and associated factors of impaired glomerular filtration among diabe...

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Bibliographic Details
Published in:Scientific reports 2024-10, Vol.14 (1), p.25143-9, Article 25143
Main Authors: Gela, Yibeltal Yismaw, Belay, Daniel Gashaneh, Belsti, Yitayeh, Getahun, Amare Belete, Getnet, Mihret, Bitew, Desalegn Anmut, Terefe, Bewuketu, Chilot, Dagmawi, Diress, Mengistie, Akalu, Yonas
Format: Article
Language:English
Subjects:
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692/308
692/4022
Adult
Aged
Blood levels
Creatinine
Creatinine - blood
Cross-Sectional Studies
Diabetes
Diabetes mellitus
Diabetes Mellitus - epidemiology
Diabetes Mellitus - physiopathology
Diabetic mellitus with hypertension
Ethiopia
Ethiopia - epidemiology
Female
Glomerular Filtration Rate
Hospitals
Humanities and Social Sciences
Humans
Hypertension
Hypertension - complications
Hypertension - epidemiology
Hypertension - physiopathology
Impaired glomerular filtration rate
Kidney diseases
Male
Middle Aged
Morbidity
multidisciplinary
Prevalence
Proteinuria
Quality of life
Referral and Consultation
Regression analysis
Renal Insufficiency, Chronic - complications
Renal Insufficiency, Chronic - epidemiology
Renal Insufficiency, Chronic - physiopathology
Risk Factors
Science
Science (multidisciplinary)
Statistical analysis
Variables
Citations: Items that this one cites
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Summary:Impaired glomerular filtration rate is common health problem in diabetic mellitus patients (DM) with hypertension (HTN). It is a major cause of morbidity, mortality, and poor quality of life. There is limited data on the prevalence and associated factors of impaired glomerular filtration among diabetic mellitus patients with hypertension in Ethiopia. Therefore, this study aimed to determine the prevalence of impaired glomerular filtration rate and associated factors among diabetic patients with hypertension in referral hospitals in Amhara Regional State, Ethiopia, 2020. An institution-based cross-sectional study was conducted in Amhara Regional referral hospitals from February 20 to April 30, 2020. Systemic sampling techniques were used to select diabetic mellitus patients with hypertension. Epi data version 3.0 was used to enter the coded data and then exported to STATA 14 for analysis. Glomerular filtration rate was estimated using the equations of collaboration with chronic kidney disease (CKD-EPI), diet modification in renal disease (MDRD-4), and creatinine clearance (CrCl). In bi-variable logistic regression, variables with a p-value of
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-024-77318-5