Metered-Dose Inhaler Spacer with Integrated Spirometer for Home-Based Asthma Monitoring and Drug Uptake

This work introduces Spiromni, a single device incorporating three different pressurised metered-dose inhaler (pMDI) accessories: a pMDI spacer, an electronic monitoring device (EMD), and a spirometer. While there are devices made to individually address the issues of technique, adherence and monito...

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Bibliographic Details
Published in:Bioengineering (Basel) 2024-05, Vol.11 (6), p.552
Main Authors: Au, Cheuk-Yan, Koh, Kelleen J X, Lim, Hui Fang, Bhagat, Ali Asgar Saleem
Format: Article
Language:English
Subjects:
Asthma
asthma control
Drug dosages
Drug therapy
Exhalation
Flow velocity
Inhalation
inhaler spacer
inhaler technique
Inhalers
Lungs
medical device
Medical innovations
Monitoring
Mortality
Patient compliance
Patients
Portable equipment
Pulmonary function tests
Pulmonary functions
Respiration
Respiratory function
Sensors
Silicones
Simulation
Spirometers
spirometry
Telemedicine
Valves
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Summary:This work introduces Spiromni, a single device incorporating three different pressurised metered-dose inhaler (pMDI) accessories: a pMDI spacer, an electronic monitoring device (EMD), and a spirometer. While there are devices made to individually address the issues of technique, adherence and monitoring, respectively, for asthma patients as laid out in the Global Initiative for Asthma's (GINA) global strategy for asthma management and prevention, Spiromni was designed to address all three issues using a single, combination device. Spiromni addresses the key challenge of measuring both inhalation and exhalation profiles, which are different by an order of magnitude. Moreover, the innovative design prevents exhalation from entering the spacer chamber and prevents medication loss during inhalation using umbrella valves without a loss in flow velocity. Apart from recording the peak exhalation flow rate, data from the sensors allow us to extract other key lung volume and capacities measures similar to a medical pulmonary function test. We believe this low-cost portable multi-functional device will benefit both asthma patients and clinicians in the management of the disease.
ISSN:2306-5354
2306-5354
DOI:10.3390/bioengineering11060552