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The Cost of Lost Productivity in an Opioid Utilizing Pain Sample
Background and Aims: Chronic pain affects more adults in the United States than any other condition. Opioid medications are widely used in the treatment of chronic pain, but there remains considerable risk and cost associated with their use. This study aims to characterize the effects of opioid pres...
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Published in: | Journal of pain research 2021-01, Vol.14, p.2347-2357 |
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description | Background and Aims: Chronic pain affects more adults in the United States than any other condition. Opioid medications are widely used in the treatment of chronic pain, but there remains considerable risk and cost associated with their use. This study aims to characterize the effects of opioid prescribing for chronic pain and similar pain conditions on lost productivity in the United States. Methods: This was a retrospective, longitudinal, observational study of chronic pain patients in 2011-2014. We identified patients with a diagnosis of musculoskeletal pain receiving index prescription for opioids in administrative claims and studied disability absence in a linked health and productivity management database. Patients were grouped as de novo and continued use opioid users before index, and by opioid dose in the year after index. Days of disability were compared before and after index with bootstrapping. Effect of opioid dose group on disability was evaluated with negative binomial regression. Lost productivity cost was compared before and after index. Results: The cohort contained 16,273 de novo and 6604 continued use patients. On average, de novo patients used 24.8 days of disability after index, an increase of 18.3 more days compared to before (p < 0.001). Continued use patients used 30.7 days after index, 9 more days than before (p < 0.001). There was a dose-response relationship between dose group and days of disability in de novo patients (p < 0.001). The weighted-average cost per person of lost productivity was $4344 higher in the year after index compared to the year before. Conclusion: Opioid prescriptions for pain patients were associated with significant disability use and lost productivity costs. With the evolution of opioid-prescribing practices, CDC recommendations, and the HHS Pain Management Best Practices, there is opportunity to use alternative pain therapies without the risks of opioid-induced side effects to improve work productivity. Keywords: opioids, pain, disability, productivity |
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Opioid medications are widely used in the treatment of chronic pain, but there remains considerable risk and cost associated with their use. This study aims to characterize the effects of opioid prescribing for chronic pain and similar pain conditions on lost productivity in the United States. Methods: This was a retrospective, longitudinal, observational study of chronic pain patients in 2011-2014. We identified patients with a diagnosis of musculoskeletal pain receiving index prescription for opioids in administrative claims and studied disability absence in a linked health and productivity management database. Patients were grouped as de novo and continued use opioid users before index, and by opioid dose in the year after index. Days of disability were compared before and after index with bootstrapping. Effect of opioid dose group on disability was evaluated with negative binomial regression. Lost productivity cost was compared before and after index. Results: The cohort contained 16,273 de novo and 6604 continued use patients. On average, de novo patients used 24.8 days of disability after index, an increase of 18.3 more days compared to before (p < 0.001). Continued use patients used 30.7 days after index, 9 more days than before (p < 0.001). There was a dose-response relationship between dose group and days of disability in de novo patients (p < 0.001). The weighted-average cost per person of lost productivity was $4344 higher in the year after index compared to the year before. Conclusion: Opioid prescriptions for pain patients were associated with significant disability use and lost productivity costs. With the evolution of opioid-prescribing practices, CDC recommendations, and the HHS Pain Management Best Practices, there is opportunity to use alternative pain therapies without the risks of opioid-induced side effects to improve work productivity. Keywords: opioids, pain, disability, productivity</description><identifier>ISSN: 1178-7090</identifier><identifier>EISSN: 1178-7090</identifier><identifier>DOI: 10.2147/JPR.S309691</identifier><identifier>PMID: 34377015</identifier><language>eng</language><publisher>Macclesfield: Dove Medical Press Limited</publisher><subject>Back pain ; Chronic pain ; Degenerative disc disease ; disability ; Drug dosages ; Economic aspects ; Employers ; Health care ; Health insurance ; Medical equipment and supplies industry ; Medical research ; Medical test kit industry ; Medicare ; Medicine, Experimental ; Morphine ; Narcotics ; Opioids ; Original Research ; pain ; Patients ; Pharmacy ; Prescription writing ; Prescriptions ; Productivity ; Public health ; Wages & salaries ; Workers compensation</subject><ispartof>Journal of pain research, 2021-01, Vol.14, p.2347-2357</ispartof><rights>COPYRIGHT 2021 Dove Medical Press Limited</rights><rights>2021. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 Fishman et al. 2021 Fishman et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c550t-d752595aac1fd5d3483b19e81e8862d4165dba16562c37d9635cc827dd0af6a03</citedby><cites>FETCH-LOGICAL-c550t-d752595aac1fd5d3483b19e81e8862d4165dba16562c37d9635cc827dd0af6a03</cites><orcidid>0000-0002-9385-785X ; 0000-0002-6051-5909 ; 0000-0001-8907-7730</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2562028558/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2562028558?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25752,27923,27924,37011,37012,44589,53790,53792,74897</link.rule.ids></links><search><creatorcontrib>Fishman, Michael A</creatorcontrib><creatorcontrib>Antony, Ajay B</creatorcontrib><creatorcontrib>Hunter, Corey W</creatorcontrib><creatorcontrib>Pope, Jason E</creatorcontrib><creatorcontrib>Staats, Peter S</creatorcontrib><creatorcontrib>Agarwal, Rahul</creatorcontrib><creatorcontrib>Connolly, Allison T</creatorcontrib><creatorcontrib>Dalal, Nirav</creatorcontrib><creatorcontrib>Deer, Timothy R</creatorcontrib><title>The Cost of Lost Productivity in an Opioid Utilizing Pain Sample</title><title>Journal of pain research</title><description>Background and Aims: Chronic pain affects more adults in the United States than any other condition. Opioid medications are widely used in the treatment of chronic pain, but there remains considerable risk and cost associated with their use. This study aims to characterize the effects of opioid prescribing for chronic pain and similar pain conditions on lost productivity in the United States. Methods: This was a retrospective, longitudinal, observational study of chronic pain patients in 2011-2014. We identified patients with a diagnosis of musculoskeletal pain receiving index prescription for opioids in administrative claims and studied disability absence in a linked health and productivity management database. Patients were grouped as de novo and continued use opioid users before index, and by opioid dose in the year after index. Days of disability were compared before and after index with bootstrapping. Effect of opioid dose group on disability was evaluated with negative binomial regression. Lost productivity cost was compared before and after index. Results: The cohort contained 16,273 de novo and 6604 continued use patients. On average, de novo patients used 24.8 days of disability after index, an increase of 18.3 more days compared to before (p < 0.001). Continued use patients used 30.7 days after index, 9 more days than before (p < 0.001). There was a dose-response relationship between dose group and days of disability in de novo patients (p < 0.001). The weighted-average cost per person of lost productivity was $4344 higher in the year after index compared to the year before. Conclusion: Opioid prescriptions for pain patients were associated with significant disability use and lost productivity costs. With the evolution of opioid-prescribing practices, CDC recommendations, and the HHS Pain Management Best Practices, there is opportunity to use alternative pain therapies without the risks of opioid-induced side effects to improve work productivity. Keywords: opioids, pain, disability, productivity</description><subject>Back pain</subject><subject>Chronic pain</subject><subject>Degenerative disc disease</subject><subject>disability</subject><subject>Drug dosages</subject><subject>Economic aspects</subject><subject>Employers</subject><subject>Health care</subject><subject>Health insurance</subject><subject>Medical equipment and supplies industry</subject><subject>Medical research</subject><subject>Medical test kit industry</subject><subject>Medicare</subject><subject>Medicine, Experimental</subject><subject>Morphine</subject><subject>Narcotics</subject><subject>Opioids</subject><subject>Original Research</subject><subject>pain</subject><subject>Patients</subject><subject>Pharmacy</subject><subject>Prescription writing</subject><subject>Prescriptions</subject><subject>Productivity</subject><subject>Public health</subject><subject>Wages & salaries</subject><subject>Workers compensation</subject><issn>1178-7090</issn><issn>1178-7090</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptkttqGzEQhpfS0hzaq77AQqEUgl0dVqeb0mB6SDHENMm1mJW0tszuypF2A-nTV1ubNi5FoBlm_vkGjaYo3mA0J7gSH76vfsxvKFJc4WfFKcZCzgRS6PkT_6Q4S2mLEJdE4ZfFCa2oEAiz0-LT7caVi5CGMjTlcrKrGOxoBv_gh8fS9yX05fXOB2_Lu8G3_qfv1-UKcuIGul3rXhUvGmiTe32w58Xdl8-3i2-z5fXXq8XlcmYYQ8PMCkaYYgAGN5ZZWklaY-UkdlJyYivMma0h35wYKqzilBkjibAWQcMB0fPias-1AbZ6F30H8VEH8Pp3IMS1hjh40zotK44VqxuKJVRgRM0MAKV10ygrMK8z6-OetRvrzlnj-iFCewQ9zvR-o9fhQUtaKVbxDHh_AMRwP7o06M4n49oWehfGpAnjiChZEZGlb_-RbsMY-zyqSUUQkYzJv6o15Af4vgm5r5mg-pILJnn-uant_D-qfKzrvAm9a3yOHxW8e1KwcdAOmxTacfChT8fCi73QxJBSdM2fYWCkpy3Tecv0YcvoL-V0v4w</recordid><startdate>20210101</startdate><enddate>20210101</enddate><creator>Fishman, Michael A</creator><creator>Antony, Ajay B</creator><creator>Hunter, Corey W</creator><creator>Pope, Jason E</creator><creator>Staats, Peter S</creator><creator>Agarwal, Rahul</creator><creator>Connolly, Allison T</creator><creator>Dalal, Nirav</creator><creator>Deer, Timothy R</creator><general>Dove Medical Press Limited</general><general>Taylor & Francis Ltd</general><general>Dove</general><general>Dove Medical Press</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7XB</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-9385-785X</orcidid><orcidid>https://orcid.org/0000-0002-6051-5909</orcidid><orcidid>https://orcid.org/0000-0001-8907-7730</orcidid></search><sort><creationdate>20210101</creationdate><title>The Cost of Lost Productivity in an Opioid Utilizing Pain Sample</title><author>Fishman, Michael A ; 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Opioid medications are widely used in the treatment of chronic pain, but there remains considerable risk and cost associated with their use. This study aims to characterize the effects of opioid prescribing for chronic pain and similar pain conditions on lost productivity in the United States. Methods: This was a retrospective, longitudinal, observational study of chronic pain patients in 2011-2014. We identified patients with a diagnosis of musculoskeletal pain receiving index prescription for opioids in administrative claims and studied disability absence in a linked health and productivity management database. Patients were grouped as de novo and continued use opioid users before index, and by opioid dose in the year after index. Days of disability were compared before and after index with bootstrapping. Effect of opioid dose group on disability was evaluated with negative binomial regression. Lost productivity cost was compared before and after index. Results: The cohort contained 16,273 de novo and 6604 continued use patients. On average, de novo patients used 24.8 days of disability after index, an increase of 18.3 more days compared to before (p < 0.001). Continued use patients used 30.7 days after index, 9 more days than before (p < 0.001). There was a dose-response relationship between dose group and days of disability in de novo patients (p < 0.001). The weighted-average cost per person of lost productivity was $4344 higher in the year after index compared to the year before. Conclusion: Opioid prescriptions for pain patients were associated with significant disability use and lost productivity costs. With the evolution of opioid-prescribing practices, CDC recommendations, and the HHS Pain Management Best Practices, there is opportunity to use alternative pain therapies without the risks of opioid-induced side effects to improve work productivity. 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subjects | Back pain Chronic pain Degenerative disc disease disability Drug dosages Economic aspects Employers Health care Health insurance Medical equipment and supplies industry Medical research Medical test kit industry Medicare Medicine, Experimental Morphine Narcotics Opioids Original Research pain Patients Pharmacy Prescription writing Prescriptions Productivity Public health Wages & salaries Workers compensation |
title | The Cost of Lost Productivity in an Opioid Utilizing Pain Sample |
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