A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean

We aimed to study time trends and levels of mean total cholesterol and lipid fractions, and dyslipidaemias prevalence in Latin America and the Caribbean (LAC). Systematic-review and meta-analysis of population-based studies in which lipid (total cholesterol [TC; 86 studies; 168,553 people], HDL-Chol...

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Bibliographic Details
Published in:eLife 2020-08, Vol.9
Main Authors: Carrillo-Larco, Rodrigo M, Benites-Moya, C Joel, Anza-Ramirez, Cecilia, Albitres-Flores, Leonardo, Sánchez-Velazco, Diana, Pacheco-Barrios, Niels, Bernabe-Ortiz, Antonio
Format: Article
Language:English
Subjects:
cardiovascular
Caribbean Region
Cholesterol
Cholesterol, HDL - metabolism
Cholesterol, LDL - metabolism
Collaboration
Confidence intervals
Data collection
Dyslipidemia
Epidemiology and Global Health
High density lipoprotein
Humans
Latin America
Lipid Metabolism
Lipids
Low density lipoprotein
Medicine
Population studies
Population-based studies
Public health
Regions
Regression analysis
risk factor
Risk factors
Systematic review
Trends
Triglycerides
Triglycerides - metabolism
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Summary:We aimed to study time trends and levels of mean total cholesterol and lipid fractions, and dyslipidaemias prevalence in Latin America and the Caribbean (LAC). Systematic-review and meta-analysis of population-based studies in which lipid (total cholesterol [TC; 86 studies; 168,553 people], HDL-Cholesterol [HDL-C; 84 studies; 121,282 people], LDL-Cholesterol [LDL-C; 61 studies; 86,854 people], and triglycerides [TG; 84 studies; 121,009 people]) levels and prevalences were laboratory-based. We used Scopus, LILACS, Embase, Medline and Global Health; studies were from 1964 to 2016. Pooled means and prevalences were estimated for lipid biomarkers from ≥2005. The pooled means (mg/dl) were 193 for TC, 120 for LDL-C, 47 for HDL-C, and 139 for TG; no strong trends. The pooled prevalence estimates were 21% for high TC, 20% for high LDL-C, 48% for low HDL-C, and 21% for high TG; no strong trends. These results may help strengthen programs for dyslipidaemias prevention/management in LAC.
ISSN:2050-084X
2050-084X
DOI:10.7554/eLife.57980