A Pregnant Woman Who Underwent Laparoscopic Adrenalectomy due to Cushing’s Syndrome

Cushing’s syndrome (CS) may lead to severe maternal and fetal morbidities and even mortalities in pregnancy. However, pregnancy complicates the diagnosis and treatment of CS. This study describes a 26-year-old pregnant woman admitted with hypertension-induced headache. Hormonal analyses performed du...

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Bibliographic Details
Published in:Case reports in endocrinology 2014-01, Vol.2014 (2014), p.1-4
Main Authors: Koc, Mehmet Sait, Aribas, Sulbiye, Karahan, Ibrahim, Akcan, Alper, Ozkan, Yusuf, Simsek, Yasin, Bayram, Fahri, Diri, Halit, Ileri, Ibrahim
Format: Article
Language:English
Subjects:
Adrenal glands
Case Report
Diabetes
Endocrinology
Fetuses
Hypertension
Laparoscopy
Medical schools
Medical treatment
NMR
Nuclear magnetic resonance
Patients
Physiology
Preeclampsia
Pregnancy
Surgery
Surgical outcomes
Tumors
Womens health
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Summary:Cushing’s syndrome (CS) may lead to severe maternal and fetal morbidities and even mortalities in pregnancy. However, pregnancy complicates the diagnosis and treatment of CS. This study describes a 26-year-old pregnant woman admitted with hypertension-induced headache. Hormonal analyses performed due to her cushingoid phenotype revealed a diagnosis of adrenocorticotropic hormone- (ACTH-) independent CS. MRI showed a 3.5 cm adenoma in her right adrenal gland. After preoperative metyrapone therapy, she underwent a successful unilateral laparoscopic adrenalectomy at 14-week gestation. Although she had a temporary postoperative adrenal insufficiency, hormonal analyses showed that she has been in remission since delivery. Findings in this patient, as well as those in previous patients, indicate that pregnancy is not an absolute contraindication for laparoscopic adrenalectomy. Rather, such surgery should be considered a safe and efficient treatment method for pregnant women with cortisol-secreting adrenal adenomas.
ISSN:2090-6501
2090-651X
DOI:10.1155/2014/283458