Giardia duodenalis Colonization Slightly Affects Gut Microbiota and Hematological Parameters in Clinically Healthy Dogs

( ) is a worldwide cause of acute diarrheal disease both in humans and animals. The primary aim of this study was to investigate possible variations in gut microbiota in a population of asymptomatic dogs ( = 31), naturally infected or not by . Gut microbiota and the hematological, biochemical, and f...

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Published in:Animals (Basel) 2023-03, Vol.13 (6), p.958
Main Authors: Peruzzo, Arianna, Vascellari, Marta, Massaro, Andrea, Mancin, Marzia, Stefani, Annalisa, Orsini, Massimiliano, Danesi, Patrizia, Petrin, Sara, Carminato, Antonio, Santoro, Michele Matteo, Speranza, Roberto, Losasso, Carmen, Capelli, Gioia
Format: Article
Language:English
Subjects:
Animals
Antiparasitic agents
Asymptomatic
Automation
Blood
Colonization
Cysts
Diarrhea
Digestive system
Dogs
Domestic animals
Feces
Giardia
Giardia duodenalis
gut
Hematology
Immunoassay
Inflammation
Intestinal microflora
Intestine
Investigations
Lipid metabolism
Lipids
Microbiota
Microorganisms
Parasites
Proteins
Software
Statistical analysis
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Summary:( ) is a worldwide cause of acute diarrheal disease both in humans and animals. The primary aim of this study was to investigate possible variations in gut microbiota in a population of asymptomatic dogs ( = 31), naturally infected or not by . Gut microbiota and the hematological, biochemical, and fecal parameters related to intestinal function were investigated. infection was associated with a significant shift of beta diversity, showing a relevant reduction of Gammaproteobacteria and an increase of Fusobacteria in male-positive dogs if compared with negatives. A significant imbalance of different bacterial taxa, with particular reference to the , , , and orders, was observed, with the first two being higher in -positive dogs. -positive males displayed significantly higher values of cCRP than negative males as well as positive females, supporting the presence of a pro-inflammatory state. Taken together, these results indicate that the presence of does not substantially modify the microbial ecology of the intestine nor the hematological markers of disease. Thus treatments against should be considered with caution in asymptomatic subjects.
ISSN:2076-2615
2076-2615
DOI:10.3390/ani13060958