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Fifteen new nucleotide substitutions in variants of human papillomavirus 18 in Korea

High-risk human papillomavirus (HPV) infection is an essential factor for the development of cervical cancer. HPV18 is the second most common carcinogenic HPV type following HPV16, but the lineages of HPV18 have been less well studied than those of HPV 16. The purpose of this study was to analyze th...

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Bibliographic Details
Published in:Virology journal 2020-05, Vol.17 (1), p.1-8
Main Authors: Kim, Namhee, Park, Jeong Su, Kim, Ji Eun, Park, Jae Hyeon, Park, Hyunwoong, Roh, Eun Youn, Yoon, Jong Hyun, Shin, Sue
Format: Article
Language:English
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Summary:High-risk human papillomavirus (HPV) infection is an essential factor for the development of cervical cancer. HPV18 is the second most common carcinogenic HPV type following HPV16, but the lineages of HPV18 have been less well studied than those of HPV 16. The purpose of this study was to analyze the nucleotide variants in the E6, E7, and L1 genes of HPV18, to assess the prevalence of HPV18 variants in Korea and to explore the relationship between HPV18 genetic variants and the risk for cervical cancer.
ISSN:1743-422X
1743-422X
DOI:10.1186/s12985-020-01337-7