Comparative Evaluation of the Therapeutic Efficacy of Microneedling Alone or Microneedling Combined with Topical 5-Fluorouracil In Localized Stable Childhood Vitiligo

Aim: The aim of this study was to evaluate and compare the therapeutic efficacy of microneedling and microneedling combined with topical 5- fluorouracil. Materials and Method: Twentyfive patients with localized stable vitiligo were treated in each group. Microneedling alone was done in control group...

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Bibliographic Details
Published in:Advances in human biology 2016, Vol.6 (1), p.25-28
Main Authors: Ghiya, BC, Soni, Prasoon, Singrodia, AnkitKumar, Chhabra, Sunny, Mehta, RD, Bai, JyotiS
Format: Article
Language:English
Subjects:
5- fluorouracil
Pigmentation
Vitiligo
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Summary:Aim: The aim of this study was to evaluate and compare the therapeutic efficacy of microneedling and microneedling combined with topical 5- fluorouracil. Materials and Method: Twentyfive patients with localized stable vitiligo were treated in each group. Microneedling alone was done in control group where as in study group microneedling combined with topical 5- fluorouracil was used which is available in form of solution with concentration of 50mg/ml. The procedure was repeated after every 15 days upto 6 months and the patients were followed up to 9 months. Results: The efficacy of treatment was higher (67.24%) and rapid in lesions treated with microneedling combined with 5-fluorouracil compared with microneedling (26.66%) alone. Conclusion: Microneedling combined with 5-fluorouracil is efficient and a better treatment in localised stable childhood vitiligo.
ISSN:2321-8568
2348-4691
DOI:10.4103/2321-8568.190142