Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases

Introduction: Acute liver failure is an uncommon condition associated with a high mortality. Most patients do not survive without liver transplantation. In the last decades, auxiliary liver transplantation has emerged as a therapeutic option. Clinical Case: The authors present two cases of acute liv...

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Bibliographic Details
Published in:GE Portuguese journal of gastroenterology 2018-12, Vol.26 (1), p.54-58
Main Authors: Perdigoto, David N., Tomé, Luís, Diogo, Dulce, Ferrão, José, Martins, Ricardo, Oliveira, Pedro, Tralhão, Guilherme, Furtado, Emanuel
Format: Article
Language:English
Subjects:
Abdomen
Acute liver failure
Auxiliary liver transplantation
Case reports
Clinical Case Study
Drug overdose
Etiology
Family medical history
Hepatitis
Hepatology
Hospitals
Immunosuppression
Liver
Liver transplantation
Liver transplants
Patients
Transplants & implants
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Summary:Introduction: Acute liver failure is an uncommon condition associated with a high mortality. Most patients do not survive without liver transplantation. In the last decades, auxiliary liver transplantation has emerged as a therapeutic option. Clinical Case: The authors present two cases of acute liver failure that required liver transplantation. Given the patients’ young age and the preserved macroscopic liver pattern evaluated in surgery, auxiliary liver transplantation was executed using different surgical approaches. Afterwards, following confirmed full native liver regeneration, the patients were submitted to auxiliary liver hepatectomy, which was accomplished without complications. Conclusion: Auxiliary liver transplantation can be regarded as an effective temporary treatment for acute liver failure in selected cases, allowing an immunosuppression-free life.
ISSN:2341-4545
2387-1954
DOI:10.1159/000487155