Serologic Abnormalities in Macular Lymphocytic Arteritis with Case Presentation

Macular lymphocytic arteritis (MLA) is an indolent cutaneous small-medium-vessel vasculitis characterized by widespread asymptomatic livedo racemosa. A number of serologic abnormalities have been reported including an elevated erythrocyte sedimentation rate and antibodies associated with antiphospho...

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Bibliographic Details
Published in:Case reports in dermatology 2022-01, Vol.14 (1), p.12-18
Main Authors: Bender, Nicole R., Bisbee, Elizabeth L., Robins, Douglas, Motaparthi, Kiran, Vincek, Vladimir
Format: Article
Language:English
Subjects:
Antibodies
Anticoagulants
antiphospholipid antibodies
Asymptomatic
Case reports
Dermatology
Histology
Histopathology
Lupus
lupus autoantibodies
lymphocytic thrombophilic arteritis
macular lymphocytic arteritis
Neutrophils
Patients
RNA polymerase
serologic abnormalities
Single Case
Womens health
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Summary:Macular lymphocytic arteritis (MLA) is an indolent cutaneous small-medium-vessel vasculitis characterized by widespread asymptomatic livedo racemosa. A number of serologic abnormalities have been reported including an elevated erythrocyte sedimentation rate and antibodies associated with antiphospholipid antibody syndrome. We present a case of MLA with multiple serologic abnormalities, including those that have yet to be reported, such as anti-U1 ribonucleotide protein, anti-RNA polymerase III, anti-smith, and anti-proteinase 3 antibodies. We also provide a brief review of this unfamiliar entity with a focus on the appropriate workup.
ISSN:1662-6567
1662-6567
DOI:10.1159/000519658