Risk factors for delayed perineal wound healing and its impact on prolonged hospital stay after abdominoperineal resection

• Published in: World journal of surgical oncology 2019-12, Vol.17 (1), p.226-226, Article 226
• Main Authors: Chang, Chu-Cheng, Lan, Yuan-Tzu, Jiang, Jeng-Kai, Chang, Shih-Ching, Yang, Shung-Haur, Lin, Chun-Chi, Lin, Hung-Hsin, Wang, Huann-Sheng, Chen, Wei-Shone, Lin, Tzu-Chen, Lin, Jen-Kou
• Format: Article
• Language: English
• Subjects: Abdomen; Abdominoperineal resection; Adenocarcinoma; Adult; Aged; Albumin; Albumins; Biomarkers, Tumor - blood; Body mass index; Clinical trials; Colorectal cancer; Complications; Complications and side effects; Diabetes; Female; Gastrointestinal diseases; Health care facilities; Heart failure; Hospital stay; Hospitals; Humans; Hypertension; Hypoalbuminemia; Hypoalbuminemia - blood; Hypoalbuminemia - diagnosis; Hypoalbuminemia - etiology; Laparoscopy; Length of Stay; Male; Medical centers; Medical records; Medical research; Middle Aged; Nutritional status; Patients; Perineal wound; Perineum - pathology; Perineum - surgery; Postoperative Complications - blood; Postoperative Complications - diagnosis; Postoperative Complications - etiology; Pressure ulcers; Primary closure; Proctectomy - adverse effects; Proctectomy - methods; Radiation therapy; Rectal Neoplasms - blood; Rectal Neoplasms - pathology; Rectal Neoplasms - surgery; Rectum; Retrospective Studies; Risk analysis; Risk Factors; Surgery; Tumors; Wound care; Wound healing; Wound Healing - physiology; Young Adult
• ISSN: 1477-7819; 1477-7819
• DOI: 10.1186/s12957-019-1768-4

Perineal wound complications are a long-lasting issue for abdominoperineal resection (APR) patients. Complication rates as high as 60% have been reported, with the most common complication being delayed perineal wound healing. The aim of this study was to identify risk factors for delayed perineal wound healing and its impact on prolonged hospital stay. We included low rectal tumor patients who underwent APR at a referral medical center from April 2002 to December 2017; a total of 229 patients were included. The basic characteristics and surgical outcomes of the patients were analyzed to identify risk factors for delayed perineal wound healing (> 30 days after APR) and prolonged hospital stay (post-APR hospital stay > 14 days). All patients received primary closure for their perineal wound. The majority of patients were diagnosed with adenocarcinoma (N = 213, 93.1%). In the univariate analysis, patients with hypoalbuminemia (albumin