The prevalence and clinical correlates of medical disorders comorbidities in patients with bipolar disorder

Medical disorders in patients with bipolar disorder (BD) have attracted more and more attention. So far, there is still a lack of studies on this issue utilizing large sample sizes in the Chinese sample. Therefore, we conducted this study to explore the clinical characteristics of BD patients comorb...

Full description

Saved in:
Bibliographic Details
Published in:BMC psychiatry 2022-03, Vol.22 (1), p.176-176, Article 176
Main Authors: Wang, Zhonggang, Li, Tao, Li, Shuhua, Li, Kunkun, Jiang, Xianfei, Wei, Chen, Yang, Lei, Cao, Haiyan, Li, Shen, Li, Jie
Format: Article
Language:English
Subjects:
Age of Onset
Bipolar disorder
Bipolar Disorder - complications
Bipolar Disorder - drug therapy
Bipolar Disorder - epidemiology
Cardiovascular diseases
Clinical features and correlates
Comorbidity
Comorbidity prevalence
Complications and side effects
Cross-Sectional Studies
Development and progression
Humans
Medical disorders
Prevalence
Prognosis
Risk factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c535t-a3bac94c272ba150631f93f7269839a65bf067837d48f2c57439257a83492b63
cites cdi_FETCH-LOGICAL-c535t-a3bac94c272ba150631f93f7269839a65bf067837d48f2c57439257a83492b63
container_end_page 176
container_issue 1
container_start_page 176
container_title BMC psychiatry
container_volume 22
creator Wang, Zhonggang
Li, Tao
Li, Shuhua
Li, Kunkun
Jiang, Xianfei
Wei, Chen
Yang, Lei
Cao, Haiyan
Li, Shen
Li, Jie
description Medical disorders in patients with bipolar disorder (BD) have attracted more and more attention. So far, there is still a lack of studies on this issue utilizing large sample sizes in the Chinese sample. Therefore, we conducted this study to explore the clinical characteristics of BD patients comorbid medical disorders in a relatively large Chinese sample. This was a cross-sectional study including 1,393 BD patients (882 patients with medical disorders and 511 patients without medical disorders). Their demographic and clinical characteristics were obtained by the Hospital Information System and self-designed questionnaires. The comorbidity rate of medical disorders in BD was 63.32%. The average number of medical disorders for a BD patient was 2.69. The top five comorbid medical disorders in BD patients were circulatory system diseases (19%), nervous system diseases (18%), endocrine and metabolic diseases (17%), digestive system diseases (16%), and respiratory system diseases (8%). BD patients with comorbid medical disorders had an older average age, lower education level, longer illness course, later onset age, lower ratio of psychotic features, more admission numbers, higher ratio of smoking and drinking alcohol, more number of manic episodes (All P 
doi_str_mv 10.1186/s12888-022-03819-0
format article
fullrecord <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_869a06601fc94a8bacfc57bba726b699</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A699116274</galeid><doaj_id>oai_doaj_org_article_869a06601fc94a8bacfc57bba726b699</doaj_id><sourcerecordid>A699116274</sourcerecordid><originalsourceid>FETCH-LOGICAL-c535t-a3bac94c272ba150631f93f7269839a65bf067837d48f2c57439257a83492b63</originalsourceid><addsrcrecordid>eNptkk1v1DAQhiMEou3CH-CAInHhkuKPxLEvSFUFpVIlLnvgZo0de9fFiRc7W8S_Z7opq66ELNnW-J1nZuS3qt5RckmpFJ8KZVLKhjDWEC6pasiL6py2PW1Y2_54-ex-Vl2Uck8I7WVHX1dnvGM9Ey07r36ut67eZfcA0U3W1TANtY1hChZibVPOLsLsSp18PbrhEB1CSXlwueD7mLIJQ5gDSsJU7wBv01zq32He1ibsUoR8THhTvfIQi3v7dK6q9dcv6-tvzd33m9vrq7vGdrybG-AGrGottmiAdkRw6hX32LCSXIHojCeil7wfWumZ7fqWK9b1IHmrmBF8Vd0u2CHBvd7lMEL-oxMEfQikvNGQ52Cj01IoIEIQ6rEgSKzrkWcMYDEjlELW54W12xuc3-JwGeIJ9PRlClu9SQ9aKiIF6xHw8QmQ06-9K7MeQ7EuRphc2hfNBJc9ox2XKP2wSDf4FzpMPiHRPsr1FfZCKfJaVF3-R4VrcGOwaXI-YPwkgS0JNqdSsvPH7inRjz7Si480-kgffIT7qnr_fO5jyj_j8L8urcPr</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2638721538</pqid></control><display><type>article</type><title>The prevalence and clinical correlates of medical disorders comorbidities in patients with bipolar disorder</title><source>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</source><source>PubMed Central (Open access)</source><creator>Wang, Zhonggang ; Li, Tao ; Li, Shuhua ; Li, Kunkun ; Jiang, Xianfei ; Wei, Chen ; Yang, Lei ; Cao, Haiyan ; Li, Shen ; Li, Jie</creator><creatorcontrib>Wang, Zhonggang ; Li, Tao ; Li, Shuhua ; Li, Kunkun ; Jiang, Xianfei ; Wei, Chen ; Yang, Lei ; Cao, Haiyan ; Li, Shen ; Li, Jie</creatorcontrib><description>Medical disorders in patients with bipolar disorder (BD) have attracted more and more attention. So far, there is still a lack of studies on this issue utilizing large sample sizes in the Chinese sample. Therefore, we conducted this study to explore the clinical characteristics of BD patients comorbid medical disorders in a relatively large Chinese sample. This was a cross-sectional study including 1,393 BD patients (882 patients with medical disorders and 511 patients without medical disorders). Their demographic and clinical characteristics were obtained by the Hospital Information System and self-designed questionnaires. The comorbidity rate of medical disorders in BD was 63.32%. The average number of medical disorders for a BD patient was 2.69. The top five comorbid medical disorders in BD patients were circulatory system diseases (19%), nervous system diseases (18%), endocrine and metabolic diseases (17%), digestive system diseases (16%), and respiratory system diseases (8%). BD patients with comorbid medical disorders had an older average age, lower education level, longer illness course, later onset age, lower ratio of psychotic features, more admission numbers, higher ratio of smoking and drinking alcohol, more number of manic episodes (All P &lt; 0.05). Smoking, numbers of depressive episode, onset age, and illness course were independent risk factors of comorbidities in BD patients (All P &lt; 0.05). Medical disorders in Chinese BD patients are highly prevalent. The smoking, number of depressive episodes, onset age, illness course, are correlated with BD patients comorbid medical disorders. Clinicians should pay attention to the medical disorders comorbidities in BD patients, and take effective measures to improve treatment outcome and reduce the suffering. The integrative approach should be the imperative in clinical practice.</description><identifier>ISSN: 1471-244X</identifier><identifier>EISSN: 1471-244X</identifier><identifier>DOI: 10.1186/s12888-022-03819-0</identifier><identifier>PMID: 35272642</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Age of Onset ; Bipolar disorder ; Bipolar Disorder - complications ; Bipolar Disorder - drug therapy ; Bipolar Disorder - epidemiology ; Cardiovascular diseases ; Clinical features and correlates ; Comorbidity ; Comorbidity prevalence ; Complications and side effects ; Cross-Sectional Studies ; Development and progression ; Humans ; Medical disorders ; Prevalence ; Prognosis ; Risk factors</subject><ispartof>BMC psychiatry, 2022-03, Vol.22 (1), p.176-176, Article 176</ispartof><rights>2022. The Author(s).</rights><rights>COPYRIGHT 2022 BioMed Central Ltd.</rights><rights>The Author(s) 2022, corrected publication 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c535t-a3bac94c272ba150631f93f7269839a65bf067837d48f2c57439257a83492b63</citedby><cites>FETCH-LOGICAL-c535t-a3bac94c272ba150631f93f7269839a65bf067837d48f2c57439257a83492b63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908627/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908627/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,37013,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35272642$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Zhonggang</creatorcontrib><creatorcontrib>Li, Tao</creatorcontrib><creatorcontrib>Li, Shuhua</creatorcontrib><creatorcontrib>Li, Kunkun</creatorcontrib><creatorcontrib>Jiang, Xianfei</creatorcontrib><creatorcontrib>Wei, Chen</creatorcontrib><creatorcontrib>Yang, Lei</creatorcontrib><creatorcontrib>Cao, Haiyan</creatorcontrib><creatorcontrib>Li, Shen</creatorcontrib><creatorcontrib>Li, Jie</creatorcontrib><title>The prevalence and clinical correlates of medical disorders comorbidities in patients with bipolar disorder</title><title>BMC psychiatry</title><addtitle>BMC Psychiatry</addtitle><description>Medical disorders in patients with bipolar disorder (BD) have attracted more and more attention. So far, there is still a lack of studies on this issue utilizing large sample sizes in the Chinese sample. Therefore, we conducted this study to explore the clinical characteristics of BD patients comorbid medical disorders in a relatively large Chinese sample. This was a cross-sectional study including 1,393 BD patients (882 patients with medical disorders and 511 patients without medical disorders). Their demographic and clinical characteristics were obtained by the Hospital Information System and self-designed questionnaires. The comorbidity rate of medical disorders in BD was 63.32%. The average number of medical disorders for a BD patient was 2.69. The top five comorbid medical disorders in BD patients were circulatory system diseases (19%), nervous system diseases (18%), endocrine and metabolic diseases (17%), digestive system diseases (16%), and respiratory system diseases (8%). BD patients with comorbid medical disorders had an older average age, lower education level, longer illness course, later onset age, lower ratio of psychotic features, more admission numbers, higher ratio of smoking and drinking alcohol, more number of manic episodes (All P &lt; 0.05). Smoking, numbers of depressive episode, onset age, and illness course were independent risk factors of comorbidities in BD patients (All P &lt; 0.05). Medical disorders in Chinese BD patients are highly prevalent. The smoking, number of depressive episodes, onset age, illness course, are correlated with BD patients comorbid medical disorders. Clinicians should pay attention to the medical disorders comorbidities in BD patients, and take effective measures to improve treatment outcome and reduce the suffering. The integrative approach should be the imperative in clinical practice.</description><subject>Age of Onset</subject><subject>Bipolar disorder</subject><subject>Bipolar Disorder - complications</subject><subject>Bipolar Disorder - drug therapy</subject><subject>Bipolar Disorder - epidemiology</subject><subject>Cardiovascular diseases</subject><subject>Clinical features and correlates</subject><subject>Comorbidity</subject><subject>Comorbidity prevalence</subject><subject>Complications and side effects</subject><subject>Cross-Sectional Studies</subject><subject>Development and progression</subject><subject>Humans</subject><subject>Medical disorders</subject><subject>Prevalence</subject><subject>Prognosis</subject><subject>Risk factors</subject><issn>1471-244X</issn><issn>1471-244X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNptkk1v1DAQhiMEou3CH-CAInHhkuKPxLEvSFUFpVIlLnvgZo0de9fFiRc7W8S_Z7opq66ELNnW-J1nZuS3qt5RckmpFJ8KZVLKhjDWEC6pasiL6py2PW1Y2_54-ex-Vl2Uck8I7WVHX1dnvGM9Ey07r36ut67eZfcA0U3W1TANtY1hChZibVPOLsLsSp18PbrhEB1CSXlwueD7mLIJQ5gDSsJU7wBv01zq32He1ibsUoR8THhTvfIQi3v7dK6q9dcv6-tvzd33m9vrq7vGdrybG-AGrGottmiAdkRw6hX32LCSXIHojCeil7wfWumZ7fqWK9b1IHmrmBF8Vd0u2CHBvd7lMEL-oxMEfQikvNGQ52Cj01IoIEIQ6rEgSKzrkWcMYDEjlELW54W12xuc3-JwGeIJ9PRlClu9SQ9aKiIF6xHw8QmQ06-9K7MeQ7EuRphc2hfNBJc9ox2XKP2wSDf4FzpMPiHRPsr1FfZCKfJaVF3-R4VrcGOwaXI-YPwkgS0JNqdSsvPH7inRjz7Si480-kgffIT7qnr_fO5jyj_j8L8urcPr</recordid><startdate>20220310</startdate><enddate>20220310</enddate><creator>Wang, Zhonggang</creator><creator>Li, Tao</creator><creator>Li, Shuhua</creator><creator>Li, Kunkun</creator><creator>Jiang, Xianfei</creator><creator>Wei, Chen</creator><creator>Yang, Lei</creator><creator>Cao, Haiyan</creator><creator>Li, Shen</creator><creator>Li, Jie</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><general>BMC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20220310</creationdate><title>The prevalence and clinical correlates of medical disorders comorbidities in patients with bipolar disorder</title><author>Wang, Zhonggang ; Li, Tao ; Li, Shuhua ; Li, Kunkun ; Jiang, Xianfei ; Wei, Chen ; Yang, Lei ; Cao, Haiyan ; Li, Shen ; Li, Jie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c535t-a3bac94c272ba150631f93f7269839a65bf067837d48f2c57439257a83492b63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Age of Onset</topic><topic>Bipolar disorder</topic><topic>Bipolar Disorder - complications</topic><topic>Bipolar Disorder - drug therapy</topic><topic>Bipolar Disorder - epidemiology</topic><topic>Cardiovascular diseases</topic><topic>Clinical features and correlates</topic><topic>Comorbidity</topic><topic>Comorbidity prevalence</topic><topic>Complications and side effects</topic><topic>Cross-Sectional Studies</topic><topic>Development and progression</topic><topic>Humans</topic><topic>Medical disorders</topic><topic>Prevalence</topic><topic>Prognosis</topic><topic>Risk factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Zhonggang</creatorcontrib><creatorcontrib>Li, Tao</creatorcontrib><creatorcontrib>Li, Shuhua</creatorcontrib><creatorcontrib>Li, Kunkun</creatorcontrib><creatorcontrib>Jiang, Xianfei</creatorcontrib><creatorcontrib>Wei, Chen</creatorcontrib><creatorcontrib>Yang, Lei</creatorcontrib><creatorcontrib>Cao, Haiyan</creatorcontrib><creatorcontrib>Li, Shen</creatorcontrib><creatorcontrib>Li, Jie</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>BMC psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Zhonggang</au><au>Li, Tao</au><au>Li, Shuhua</au><au>Li, Kunkun</au><au>Jiang, Xianfei</au><au>Wei, Chen</au><au>Yang, Lei</au><au>Cao, Haiyan</au><au>Li, Shen</au><au>Li, Jie</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The prevalence and clinical correlates of medical disorders comorbidities in patients with bipolar disorder</atitle><jtitle>BMC psychiatry</jtitle><addtitle>BMC Psychiatry</addtitle><date>2022-03-10</date><risdate>2022</risdate><volume>22</volume><issue>1</issue><spage>176</spage><epage>176</epage><pages>176-176</pages><artnum>176</artnum><issn>1471-244X</issn><eissn>1471-244X</eissn><abstract>Medical disorders in patients with bipolar disorder (BD) have attracted more and more attention. So far, there is still a lack of studies on this issue utilizing large sample sizes in the Chinese sample. Therefore, we conducted this study to explore the clinical characteristics of BD patients comorbid medical disorders in a relatively large Chinese sample. This was a cross-sectional study including 1,393 BD patients (882 patients with medical disorders and 511 patients without medical disorders). Their demographic and clinical characteristics were obtained by the Hospital Information System and self-designed questionnaires. The comorbidity rate of medical disorders in BD was 63.32%. The average number of medical disorders for a BD patient was 2.69. The top five comorbid medical disorders in BD patients were circulatory system diseases (19%), nervous system diseases (18%), endocrine and metabolic diseases (17%), digestive system diseases (16%), and respiratory system diseases (8%). BD patients with comorbid medical disorders had an older average age, lower education level, longer illness course, later onset age, lower ratio of psychotic features, more admission numbers, higher ratio of smoking and drinking alcohol, more number of manic episodes (All P &lt; 0.05). Smoking, numbers of depressive episode, onset age, and illness course were independent risk factors of comorbidities in BD patients (All P &lt; 0.05). Medical disorders in Chinese BD patients are highly prevalent. The smoking, number of depressive episodes, onset age, illness course, are correlated with BD patients comorbid medical disorders. Clinicians should pay attention to the medical disorders comorbidities in BD patients, and take effective measures to improve treatment outcome and reduce the suffering. The integrative approach should be the imperative in clinical practice.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>35272642</pmid><doi>10.1186/s12888-022-03819-0</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1471-244X
ispartof BMC psychiatry, 2022-03, Vol.22 (1), p.176-176, Article 176
issn 1471-244X
1471-244X
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_869a06601fc94a8bacfc57bba726b699
source Publicly Available Content Database (Proquest) (PQ_SDU_P3); PubMed Central (Open access)
subjects Age of Onset
Bipolar disorder
Bipolar Disorder - complications
Bipolar Disorder - drug therapy
Bipolar Disorder - epidemiology
Cardiovascular diseases
Clinical features and correlates
Comorbidity
Comorbidity prevalence
Complications and side effects
Cross-Sectional Studies
Development and progression
Humans
Medical disorders
Prevalence
Prognosis
Risk factors
title The prevalence and clinical correlates of medical disorders comorbidities in patients with bipolar disorder
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T10%3A49%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20prevalence%20and%20clinical%20correlates%20of%20medical%20disorders%20comorbidities%20in%20patients%20with%20bipolar%20disorder&rft.jtitle=BMC%20psychiatry&rft.au=Wang,%20Zhonggang&rft.date=2022-03-10&rft.volume=22&rft.issue=1&rft.spage=176&rft.epage=176&rft.pages=176-176&rft.artnum=176&rft.issn=1471-244X&rft.eissn=1471-244X&rft_id=info:doi/10.1186/s12888-022-03819-0&rft_dat=%3Cgale_doaj_%3EA699116274%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c535t-a3bac94c272ba150631f93f7269839a65bf067837d48f2c57439257a83492b63%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2638721538&rft_id=info:pmid/35272642&rft_galeid=A699116274&rfr_iscdi=true