Ceftriaxone for the Treatment of Chronic Bacterial Prostatitis: A Case Series and Literature Review

Chronic bacterial prostatitis is increasingly difficult to treat due to rising antimicrobial resistance limiting oral treatment options. In this case series, 11 men with CBP (including patients with urological comorbidities) due to multi-resistant were treated with once-daily ceftriaxone intravenous...

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Bibliographic Details
Published in:Antibiotics (Basel) 2022-01, Vol.11 (1), p.83
Main Authors: Kuiper, Sander G, Ploeger, Maarten, Wilms, Erik B, van Dijk, Marleen M, Leegwater, Emiel, Huis In't Veld, Robert A G, van Nieuwkoop, Cees
Format: Article
Language:English
Subjects:
Antibiotics
Antimicrobial resistance
Bacteria
Bioassays
Biopsy
Brief Report
Catheters
Ceftriaxone
Chromatography
chronic bacterial prostatitis
Chronic infection
Disease prevention
Drug dosages
E coli
Escherichia coli
Literature reviews
Patients
Pharmacokinetics
Phlebitis
Prostate
Prostatitis
Side effects
Urinary tract diseases
Urinary tract infections
Urogenital system
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Summary:Chronic bacterial prostatitis is increasingly difficult to treat due to rising antimicrobial resistance limiting oral treatment options. In this case series, 11 men with CBP (including patients with urological comorbidities) due to multi-resistant were treated with once-daily ceftriaxone intravenously for 6 weeks. Nine patients were clinically cured at 3 months follow up. No early withdrawal of medication due to side effects occurred. A literature review was conducted to describe the prostate pharmacokinetics of ceftriaxone and its use in prostatic infection. In conclusion, ceftriaxone can be considered an appropriate treatment of chronic bacterial prostatitis.
ISSN:2079-6382
2079-6382
DOI:10.3390/antibiotics11010083