Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications

Hydrogels are being investigated for their application in inducing the regeneration of various tissues, and suitable conditions for each tissue are becoming more apparent. Conditions such as the mechanical properties, degradation period, degradation mechanism, and cell affinity can be tailored by ch...

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Bibliographic Details
Published in:Biomolecules (Basel, Switzerland) Switzerland), 2023-02, Vol.13 (2), p.280
Main Authors: Hama, Rikako, Ulziibayar, Anudari, Reinhardt, James W, Watanabe, Tatsuya, Kelly, John, Shinoka, Toshiharu
Format: Article
Language:English
Subjects:
3-D printers
Biocompatibility
Biocompatible Materials - chemistry
Biodegradable materials
Biodegradation
Biological activity
Biopolymers
Chemical properties
collagen
Drug delivery
drug delivery system (DDS)
Drug Delivery Systems
Drugs
Gels (Pharmacy)
hydrogel
Hydrogels
Hydrogels - chemistry
Mechanical properties
Molecular weight
Physical properties
Polymers
Review
silk fibroin
Testing
Tissue Engineering
Vehicles
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Summary:Hydrogels are being investigated for their application in inducing the regeneration of various tissues, and suitable conditions for each tissue are becoming more apparent. Conditions such as the mechanical properties, degradation period, degradation mechanism, and cell affinity can be tailored by changing the molecular structure, especially in the case of polymers. Furthermore, many high-functional hydrogels with drug delivery systems (DDSs), in which drugs or bioactive substances are contained in controlled hydrogels, have been reported. This review focuses on the molecular design and function of biopolymer-based hydrogels and introduces recent developments in functional hydrogels for clinical applications.
ISSN:2218-273X
2218-273X
DOI:10.3390/biom13020280