Neurobiology of Aggressive Behavior-Role of Autoantibodies Reactive With Stress-Related Peptide Hormones

Adrenocorticotropic hormone together with arginine vasopressin and oxytocin, the neuropeptides regulating the stress response and the hypothalamic-pituitary-adrenal axis activity, are known to modulate aggressive behavior. The functional role of the adrenocorticotropic hormone immunoglobulin G autoa...

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Bibliographic Details
Published in:Frontiers in psychiatry 2019-12, Vol.10, p.872-872
Main Authors: Vaeroy, Henning, Schneider, Frida, Fetissov, Sergueï O
Format: Article
Language:English
Subjects:
adrenocorticotropic hormone
autoantibodies
human aggression
hypothalamic-pituitary-adrenal axis
oxytocin
Psychiatry
vasopressin
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Summary:Adrenocorticotropic hormone together with arginine vasopressin and oxytocin, the neuropeptides regulating the stress response and the hypothalamic-pituitary-adrenal axis activity, are known to modulate aggressive behavior. The functional role of the adrenocorticotropic hormone immunoglobulin G autoantibodies in peptidergic signaling and motivated behavior, including aggression, has been shown in experimental and models. This review summarizes some experimental data implicating autoantibodies reactive with stress-related peptides in aggressive behavior.
ISSN:1664-0640
1664-0640
DOI:10.3389/fpsyt.2019.00872