The Composition of Subgingival Microbiome in Hidradenitis Suppurativa and Periodontitis Patients

Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of the pilosebaceous unit of the intertriginous body areas. Recent findings have suggested the association between periodontitis and HS. This investigation aimed to characterize and compare the composition of subgingival microbiome bet...

Full description

Saved in:
Bibliographic Details
Published in:Pathogens (Basel) 2023-02, Vol.12 (3), p.377
Main Authors: Jastrząb, Beata, Paśnik-Chwalik, Barbara, Dębska-Łasut, Katarzyna, Konopka, Tomasz, Krajewski, Piotr K, Szepietowski, Jacek C, Matusiak, Łukasz
Format: Article
Language:English
Subjects:
Bacteria
Composition
Disease
Gingiva
Health aspects
hidradenitis suppurativa
Inflammatory diseases
Microbiomes
Microbiota
Microbiota (Symbiotic organisms)
oral microbiota
Pathogens
periodontal health
Periodontitis
Psoriasis
Psoriatic arthritis
Rheumatoid arthritis
Risk factors
Skin
Skin diseases
subgingival microbiome
Teeth
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of the pilosebaceous unit of the intertriginous body areas. Recent findings have suggested the association between periodontitis and HS. This investigation aimed to characterize and compare the composition of subgingival microbiome between HS, periodontitis, and control patients. The nine crucial perio-pathogenic species and total bacteria were analyzed using RT-PCR based tests in samples collected from 30 patients with periodontitis, 30 patients with HS and 30 controls. Patients with HS were excluded if they had periodontitis and patients with periodontitis were excluded if they had HS. The mean total bacteria count was significantly higher in HS and periodontitis samples than in control samples ( < 0.05). The majority of perio-pathogens tested were more frequently detected in HS and periodontitis groups than among controls. was the most common pathogen in individuals with HS (70%) and periodontitis (86.7%), while among controls was the most frequently detected isolate (33.2%). The results of the present investigation demonstrated that HS and periodontitis patients share some similarities in their subgingival microbiome composition.
ISSN:2076-0817
2076-0817
DOI:10.3390/pathogens12030377