Healthcare resources and costs associated with nonvalvular atrial fibrillation in Spain: apixaban versus acenocoumarol

Healthcare resources usage and costs associated to nonvalvular atrial fibrillation (NVAF) were analyzed in Spain. This is an observational and retrospective study on patients with NVAF who started their treatment with apixaban or acenocoumarol between 1 January 2015 and 31 December 2017. 2160 patien...

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Bibliographic Details
Published in:Journal of comparative effectiveness research 2023-08, Vol.12 (8), p.e230007-e230007
Main Authors: Colet, Josep Comín, Mainar, Antoni Sicras, Salazar-Mendiguchía, Joel, Del Campo Alonso, María Isabel, Echeto, Ainara, Larena, David Vilanova, Sánchez, Olga Delgado
Format: Article
Language:English
Subjects:
acenocoumarol
apixaban
cardiovascular events
cost–effectiveness
healthcare resources
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Summary:Healthcare resources usage and costs associated to nonvalvular atrial fibrillation (NVAF) were analyzed in Spain. This is an observational and retrospective study on patients with NVAF who started their treatment with apixaban or acenocoumarol between 1 January 2015 and 31 December 2017. 2160 patients treated with apixaban were paired (1:1) with patients treated with acenocoumarol (propensity score matching). Apixaban reduced the incidence of strokes and systemic embolisms, minor and major bleedings and deaths, versus acenocoumarol. Apixaban led to reductions of 80, 55 and 43% in costs related to nursing visits, hospitalizations, and emergency visits, respectively, leading to annual cost savings of €274/patient, from the perspective of society. Our results suggested that apixaban is a cost-effective alternative for patients with NVAF.
ISSN:2042-6305
2042-6313
DOI:10.57264/cer-2023-0007