Psychache and Suicidal History in Patients with Obsessive-Compulsive Disorder

• Published in: Neuropsychiatric disease and treatment 2019-12, Vol.15, p.3531-3539
• Main Authors: Demirkol, Mehmet Emin, Namlı, Zeynep, Eriş Davul, Özge, Karaytuğ, Mahmut Onur, Tamam, Lut, Yılmaz, Hamdi
• Format: Article
• Language: English
• Subjects: Ambulatory care facilities; Analysis; Care and treatment; College faculty; Comorbidity; Contamination; Death; Depression (Mood disorder); Diagnosis; Education; Emotional disorders; Health aspects; Health care; Hydrogen sulfide; Marriage; Medical research; Mental depression; Mental disorders; Mood disorders; Neuroses; Obsessive compulsive disorder; Original Research; Pain; Patients; psychache; psychological pain; Psychosis; Regression analysis; Risk factors; Sociodemographics; Statistical analysis; Suicidal behavior; Suicide; Suicides & suicide attempts; Validity; Variables
• ISSN: 1176-6328; 1178-2021; 1178-2021
• DOI: 10.2147/NDT.S237369

Suicide is an important cause of death in patients diagnosed with obsessive-compulsive disorder (OCD) as well as other psychiatric disorders. Early determining of risk factors provides an opportunity for intervention. The mediating effect of psychological pain (also known as psychache) on suicide has been shown in various disorders but has not been investigated in patients with OCD. In this study, we aimed to show the relationship between psychological pain and other clinical variables and suicide in OCD patients. This cross-sectional study consisted of 67 patients diagnosed with OCD according to DSM-5 criteria with no comorbid psychiatric diagnosis who applied to the psychiatric outpatient clinic of Çukurova University Faculty of Medicine and 63 healthy controls. Among the OCD patients, 12 had previous suicide attempts. In addition to the sociodemographic data form, participants filled out the Yale-Brown Obsessive Compulsive Scale (YBOCS), the Psychache Scale (PS), the Beck Scale for Suicidal Ideation (BSIS), and the Hamilton Depression Scale (HDS). OCD group's median obsession, compulsion, and the total scores of YBOCS, and the mean PS scores were higher than the control group. There was no difference between the sociodemographic variables of OCD patients with and without previous suicide attempts such as age, gender, years of education, place of residence, marital, and occupational status. The median scores of obsession, avoidance, global severity, and indecisiveness subdimensions of YBOCS, the mean BSIS and PS scores, the rates of current aggressive, current contamination, and the past religious obsessions were higher in the suicidal group. There were moderately significant relationships in the same direction between the PS, BSIS, and total YBOCS scores. Multivariate regression analysis demonstrated that only the PS scores predicted previous suicide attempts. Our results demonstrated that current aggressive, current contamination, past religious obsessions, and the higher psychological pain are related to previous suicide attempts in OCD patients. Our regression analysis supports Shneidman's hypothesis: there would be no suicide without psychache. Relieving psychache in OCD patients may reduce suicide attempts even if there is no diagnosis of comorbid depression.