Association of epicardial fat thickness with left ventricular diastolic function parameters in a community population

• Published in: BMC cardiovascular disorders 2021-05, Vol.21 (1), p.262-262, Article 262
• Main Authors: Ma, Wei, Zhang, Baowei, Yang, Ying, Qi, Litong, Zhou, Jin, Li, Min, Jia, Jia, Zhang, Yan, Yong, Huo
• Format: Article
• Language: English
• Subjects: Adipose Tissue - diagnostic imaging; Adipose Tissue - physiopathology; Adipose tissues; Adiposity; Adult; Age; Aged; Aorta; Beijing - epidemiology; Body mass index; Cardiovascular disease; Cardiovascular diseases; Care and treatment; Coronary artery disease; Coronary vessels; Diabetes; Diabetes mellitus; Diagnosis; Diastole; Diastolic function; Doppler effect; Echocardiography; Echocardiography, Doppler; Epicardial fat; Female; Glucose; Health aspects; Heart diseases; Heart rate; Humans; Hypertension; Left ventricle; Left ventricular function; Male; Metabolic syndrome; Middle Aged; Mortality; Obesity; Pericardium - diagnostic imaging; Pericardium - physiopathology; Population; Predictive Value of Tests; Prevalence; Regression analysis; Risk Factors; Thickness; Ventricle; Ventricular Dysfunction, Left - diagnostic imaging; Ventricular Dysfunction, Left - epidemiology; Ventricular Dysfunction, Left - physiopathology; Ventricular Function, Left
• ISSN: 1471-2261; 1471-2261
• DOI: 10.1186/s12872-021-02071-w

We examined the relationship between epicardial fat thickness (EFT) measured by echocardiography and left ventricular diastolic function parameters in a Beijing community population. We included 1004 participants in this study. Echocardiographic parameters including E and A peak velocity, the early diastolic velocities (e') of the septal and lateral mitral annulus using tissue doppler imaging, E/e', and EFT were measured. EFT1 was measured perpendicularly on the right ventricular free wall at end diastole in the extension line of the aortic root. EFT2 was the maximum thickness measured perpendicularly on the right ventricular free wall at end diastole. Multivariable linear regression was used to analyze the relationship between EFT and the mean e' and E/e'. The mean age of the participants was 63.91 ± 9.02 years, and 51.4% were men. EFT1 and EFT2 were negatively correlated with lateral e', septal e', and mean e' (p