Selective Laser Trabeculoplasty vs. Fixed Combinations with Timolol in Practice: A Replacement Study in Primary Open Angle Glaucoma

• Published in: Turk oftalmoloji gazetesi 2017-08, Vol.47 (4), p.198-204
• Main Authors: Tufan, Ali Kutlay, Onur, İsmail Umut, Yiğit, Fadime Ulviye, Ağaçhan, Ahmet, Aşık Nacaroğlu, Şenay
• Format: Article
• Language: English
• Subjects: Analysis; Appointments & personnel changes; Care and treatment; Comparative analysis; Dosage and administration; Fixed combination antiglaucoma medications; Glaucoma; Hypertension; intraocular pressure reduction rate; Lasers; Open-angle glaucoma; Original; Patients; primary open-angle glaucoma; Rapid prototyping; selective laser trabeculoplasty; Timolol maleate; Tıp; Trabeculectomy; Treatment outcome
• ISSN: 2149-8695; 1300-0659; 2147-2661; 2149-8709
• DOI: 10.4274/tjo.87300

To evaluate the potential of selective laser trabeculoplasty (SLT) in two arms (360˚ vs. 180˚) as a replacement for fixed combinations (FCs) with timolol in primary open angle glaucoma over 6 months. Of 40 patients in a prospective, comparative, interventional case series, 18 eyes and 22 eyes were randomized to SLT 180º and SLT 360º groups, respectively, along with 40 fellow-control eyes. FC with timolol was discontinued on the day of treatment for the eye to be operated on, while ongoing therapy was not interrupted for the contralateral eye. Eyes were examined for intraocular pressure (IOP) elevation 1 hour and 1 day after SLT. The follow-up visits were then scheduled for 1 week, 1 month, 3 months, and 6 months after, during the which the IOP of both eyes and any possible complications were evaluated. There were no statistically significant differences in mean IOPs through 6 months among the groups with exception of postlaser 1 hour and postlaser 1 day (p