A Miniaturized QuEChERS Method Combined with Ultrahigh Liquid Chromatography Coupled to Tandem Mass Spectrometry for the Analysis of Pyrrolizidine Alkaloids in Oregano Samples

Recent and unexpected food alerts about relatively high amounts of pyrrolizidine alkaloids in oregano samples have stressed the need to develop analytical strategies to ensure food safety in this type of foodstuff. Accordingly, this work presents the development of a miniaturized strategy based on t...

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Bibliographic Details
Published in:Foods 2020-09, Vol.9 (9), p.1319
Main Authors: Izcara, Sergio, Casado, Natalia, Morante-Zarcero, Sonia, Sierra, Isabel
Format: Article
Language:English
Subjects:
aromatic herbs
miniaturization
natural toxins
oregano
pyrrolizidine alkaloids
UHPLC-MS/MS
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Summary:Recent and unexpected food alerts about relatively high amounts of pyrrolizidine alkaloids in oregano samples have stressed the need to develop analytical strategies to ensure food safety in this type of foodstuff. Accordingly, this work presents the development of a miniaturized strategy based on the QuEChERS (quick, easy, cheap, effective, rugged and safe) method combined with ultrahigh liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) for the determination of 21 pyrrolizidine alkaloids suggested by the European Food Safety Authority to be monitored in food. The analytical method was properly validated, with overall average recoveries from 77 to 96% and relative standard deviations
ISSN:2304-8158
2304-8158
DOI:10.3390/foods9091319